Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3770c

Experiment: 7H9 with nitrite 5 mM

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 5 mM
4,214,254	+		Rv3768	0.51	+0.7
4,214,254	+		Rv3768	0.51	+0.2
4,214,276	-		Rv3768	0.57	-0.3
4,214,302	+		Rv3768	0.64	-0.2
4,214,472	+				-0.7
4,214,473	-				+0.7
4,214,555	+				-1.1
4,214,556	-				-0.6
4,215,064	+				-0.5
4,215,201	+				+1.7
4,215,202	-				-0.9
4,215,339	+		Rv3770c	0.24	+0.5
4,215,710	+		Rv3770c	0.89	+2.3
4,215,714	+		Rv3770c	0.89	-2.0
4,215,714	+		Rv3770c	0.89	-0.7
4,215,714	+		Rv3770c	0.89	-1.0
4,215,714	+		Rv3770c	0.89	+0.1
4,215,714	+		Rv3770c	0.89	-0.5
4,215,714	+		Rv3770c	0.89	-0.1
4,215,715	-		Rv3770c	0.89	+1.8
4,215,715	-		Rv3770c	0.89	-0.5
4,215,718	-				-0.8
4,215,746	-				-0.1
4,215,762	-				+0.1
4,215,762	-				-0.2
4,215,770	-				+0.4
4,215,778	+				-0.6
4,215,779	-				+1.0
4,216,079	+				-0.6
4,216,080	-				-0.3
4,216,105	-		Rv3770B	0.14	+0.6
4,216,105	-		Rv3770B	0.14	+1.0
4,216,278	-				-0.1
4,216,525	+		Rv3771c	0.37	-0.1
4,216,526	-		Rv3771c	0.37	-0.3
4,216,743	+				+0.5
4,216,743	+				-1.6
4,216,744	-				-0.3
4,216,744	-				-0.2
4,216,744	-				-0.6