Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3759c

Experiment: 7H9 with nitrite 5 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3758c and Rv3759c are separated by 8 nucleotidesRv3759c and Rv3760 are separated by 164 nucleotidesRv3760 and Rv3761c are separated by 21 nucleotides Rv3758c: Rv3758c - Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport ATP-binding protein ABC transporter ProV, at 4,203,287 to 4,204,417 Rv3758c Rv3759c: Rv3759c - Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) binding lipoprotein ProX, at 4,204,426 to 4,205,373 Rv3759c Rv3760: Rv3760 - Possible conserved membrane protein, at 4,205,538 to 4,205,840 Rv3760 Rv3761c: Rv3761c - Possible acyl-CoA dehydrogenase FadE36, at 4,205,862 to 4,206,917 Rv3761c Position (kb) 4204 4205 4206Strain fitness (log2 ratio) -3 -2 -1 0 1at 4203.884 kb on + strand, within Rv3758cat 4203.885 kb on - strand, within Rv3758cat 4203.885 kb on - strand, within Rv3758cat 4203.896 kb on + strand, within Rv3758cat 4203.897 kb on - strand, within Rv3758cat 4204.179 kb on + strand, within Rv3758cat 4204.427 kb on + strandat 4204.803 kb on - strand, within Rv3759cat 4204.803 kb on - strand, within Rv3759cat 4205.007 kb on - strand, within Rv3759cat 4205.007 kb on - strand, within Rv3759cat 4205.060 kb on + strand, within Rv3759cat 4205.080 kb on - strand, within Rv3759cat 4205.127 kb on - strand, within Rv3759cat 4205.127 kb on - strand, within Rv3759cat 4205.426 kb on - strandat 4205.719 kb on + strand, within Rv3760at 4205.730 kb on - strand, within Rv3760at 4206.049 kb on - strand, within Rv3761cat 4206.073 kb on + strand, within Rv3761cat 4206.074 kb on - strand, within Rv3761cat 4206.141 kb on + strand, within Rv3761cat 4206.142 kb on - strand, within Rv3761cat 4206.142 kb on - strand, within Rv3761cat 4206.165 kb on + strand, within Rv3761cat 4206.166 kb on - strand, within Rv3761c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 5 mM
remove
4,203,884 + Rv3758c 0.53 -0.9
4,203,885 - Rv3758c 0.53 -0.6
4,203,885 - Rv3758c 0.53 -1.0
4,203,896 + Rv3758c 0.54 -2.5
4,203,897 - Rv3758c 0.54 -0.5
4,204,179 + Rv3758c 0.79 +1.0
4,204,427 + -0.5
4,204,803 - Rv3759c 0.40 -0.5
4,204,803 - Rv3759c 0.40 +0.3
4,205,007 - Rv3759c 0.61 -1.1
4,205,007 - Rv3759c 0.61 +1.7
4,205,060 + Rv3759c 0.67 -0.9
4,205,080 - Rv3759c 0.69 -0.8
4,205,127 - Rv3759c 0.74 -0.0
4,205,127 - Rv3759c 0.74 -2.8
4,205,426 - -1.7
4,205,719 + Rv3760 0.60 +0.3
4,205,730 - Rv3760 0.63 -0.4
4,206,049 - Rv3761c 0.18 -1.2
4,206,073 + Rv3761c 0.20 +0.4
4,206,074 - Rv3761c 0.20 +0.6
4,206,141 + Rv3761c 0.26 -0.7
4,206,142 - Rv3761c 0.27 -1.8
4,206,142 - Rv3761c 0.27 -2.9
4,206,165 + Rv3761c 0.29 +0.1
4,206,166 - Rv3761c 0.29 +0.1

Or see this region's nucleotide sequence