Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3417c

Experiment: 7H9 with nitrite 5 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3415c and Rv3416 are separated by 370 nucleotidesRv3416 and Rv3417c are separated by 71 nucleotidesRv3417c and Rv3418c are separated by 94 nucleotidesRv3418c and Rv3419c are separated by 266 nucleotides Rv3415c: Rv3415c - Conserved hypothetical protein, at 3,833,694 to 3,834,521 Rv3415c Rv3416: Rv3416 - Transcriptional regulatory protein WhiB-like WhiB3. Contains [4FE-4S] cluster., at 3,834,892 to 3,835,200 Rv3416 Rv3417c: Rv3417c - 60 kDa chaperonin 1 GroEL1 (protein CPN60-1) (GroEL protein 1), at 3,835,272 to 3,836,891 Rv3417c Rv3418c: Rv3418c - 10 kDa chaperonin GroES (protein CPN10) (protein GroES) (BCG-a heat shock protein) (10 kDa antigen), at 3,836,986 to 3,837,288 Rv3418c Rv3419c: Rv3419c - Probable O-sialoglycoprotein endopeptidase Gcp (glycoprotease), at 3,837,555 to 3,838,589 Rv3419c Position (kb) 3835 3836 3837Strain fitness (log2 ratio) -2 -1 0 1 2at 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.361 kb on + strand, within Rv3415cat 3834.438 kb on + strand, within Rv3415cat 3834.649 kb on + strandat 3834.785 kb on - strandat 3835.148 kb on + strand, within Rv3416at 3835.148 kb on + strand, within Rv3416at 3835.148 kb on + strand, within Rv3416at 3835.198 kb on + strandat 3835.199 kb on - strandat 3835.392 kb on - strandat 3835.392 kb on - strandat 3835.438 kb on + strand, within Rv3417cat 3835.439 kb on - strand, within Rv3417cat 3835.477 kb on - strand, within Rv3417cat 3836.043 kb on - strand, within Rv3417cat 3836.059 kb on + strand, within Rv3417cat 3836.290 kb on + strand, within Rv3417cat 3836.291 kb on - strand, within Rv3417cat 3836.873 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 5 mM
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3,834,296 + Rv3415c 0.73 +0.6
3,834,296 + Rv3415c 0.73 -0.7
3,834,296 + Rv3415c 0.73 +0.1
3,834,296 + Rv3415c 0.73 -1.9
3,834,296 + Rv3415c 0.73 +0.6
3,834,296 + Rv3415c 0.73 +2.5
3,834,296 + Rv3415c 0.73 +0.2
3,834,296 + Rv3415c 0.73 +0.9
3,834,361 + Rv3415c 0.81 -1.2
3,834,438 + Rv3415c 0.90 -0.4
3,834,649 + +0.2
3,834,785 - +0.7
3,835,148 + Rv3416 0.83 -1.2
3,835,148 + Rv3416 0.83 -1.0
3,835,148 + Rv3416 0.83 -1.0
3,835,198 + -0.9
3,835,199 - -1.9
3,835,392 - -1.1
3,835,392 - -0.5
3,835,438 + Rv3417c 0.10 -0.6
3,835,439 - Rv3417c 0.10 -1.6
3,835,477 - Rv3417c 0.13 +0.1
3,836,043 - Rv3417c 0.48 -0.2
3,836,059 + Rv3417c 0.49 -0.2
3,836,290 + Rv3417c 0.63 -2.4
3,836,291 - Rv3417c 0.63 -1.3
3,836,873 - -0.0

Or see this region's nucleotide sequence