Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2622

Experiment: 7H9 with nitrite 5 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2620c and Rv2621c overlap by 4 nucleotidesRv2621c and Rv2622 are separated by 77 nucleotidesRv2622 and Rv2623 are separated by 135 nucleotides Rv2620c: Rv2620c - Probable conserved transmembrane protein, at 2,947,462 to 2,947,887 Rv2620c Rv2621c: Rv2621c - Possible transcriptional regulatory protein, at 2,947,884 to 2,948,558 Rv2621c Rv2622: Rv2622 - Possible methyltransferase (methylase), at 2,948,636 to 2,949,457 Rv2622 Rv2623: Rv2623 - Universal stress protein family protein TB31.7, at 2,949,593 to 2,950,486 Rv2623 Position (kb) 2948 2949 2950Strain fitness (log2 ratio) -1 0 1at 2948.007 kb on + strand, within Rv2621cat 2948.007 kb on + strand, within Rv2621cat 2948.558 kb on + strandat 2948.559 kb on - strandat 2948.635 kb on + strandat 2948.635 kb on + strandat 2948.635 kb on + strandat 2948.635 kb on + strandat 2948.635 kb on + strandat 2948.636 kb on - strandat 2948.873 kb on + strand, within Rv2622at 2948.873 kb on + strand, within Rv2622at 2949.277 kb on - strand, within Rv2622at 2949.485 kb on + strandat 2949.623 kb on - strandat 2949.735 kb on + strand, within Rv2623at 2950.080 kb on + strand, within Rv2623at 2950.081 kb on - strand, within Rv2623at 2950.081 kb on - strand, within Rv2623

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 5 mM
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2,948,007 + Rv2621c 0.18 +0.3
2,948,007 + Rv2621c 0.18 +0.3
2,948,558 + +0.8
2,948,559 - -0.8
2,948,635 + +0.1
2,948,635 + +1.7
2,948,635 + -0.3
2,948,635 + +0.4
2,948,635 + +0.2
2,948,636 - -0.4
2,948,873 + Rv2622 0.29 -1.6
2,948,873 + Rv2622 0.29 -1.3
2,949,277 - Rv2622 0.78 -0.5
2,949,485 + +0.3
2,949,623 - -0.2
2,949,735 + Rv2623 0.16 -0.6
2,950,080 + Rv2623 0.54 +0.9
2,950,081 - Rv2623 0.55 -0.7
2,950,081 - Rv2623 0.55 -1.2

Or see this region's nucleotide sequence