Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1663

Experiment: 7H9 with nitrite 5 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1662 and Rv1663 overlap by 1 nucleotidesRv1663 and Rv1664 are separated by 5 nucleotides Rv1662: Rv1662 - Probable polyketide synthase Pks8, at 1,881,704 to 1,886,512 Rv1662 Rv1663: Rv1663 - Probable polyketide synthase Pks17, at 1,886,512 to 1,888,020 Rv1663 Rv1664: Rv1664 - Probable polyketide synthase Pks9, at 1,888,026 to 1,891,079 Rv1664 Position (kb) 1886 1887 1888 1889Strain fitness (log2 ratio) -1 0 1at 1887.416 kb on + strand, within Rv1663at 1887.545 kb on + strand, within Rv1663at 1887.545 kb on + strand, within Rv1663at 1887.549 kb on - strand, within Rv1663at 1887.549 kb on - strand, within Rv1663at 1887.549 kb on - strand, within Rv1663at 1887.549 kb on - strand, within Rv1663at 1887.553 kb on - strand, within Rv1663at 1887.825 kb on - strand, within Rv1663at 1888.608 kb on - strand, within Rv1664at 1888.611 kb on + strand, within Rv1664at 1888.642 kb on + strand, within Rv1664at 1888.851 kb on + strand, within Rv1664at 1888.852 kb on - strand, within Rv1664at 1888.852 kb on - strand, within Rv1664

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 5 mM
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1,887,416 + Rv1663 0.60 +0.1
1,887,545 + Rv1663 0.68 +0.6
1,887,545 + Rv1663 0.68 -0.6
1,887,549 - Rv1663 0.69 +0.4
1,887,549 - Rv1663 0.69 +0.0
1,887,549 - Rv1663 0.69 -0.6
1,887,549 - Rv1663 0.69 -0.9
1,887,553 - Rv1663 0.69 +0.9
1,887,825 - Rv1663 0.87 -0.2
1,888,608 - Rv1664 0.19 -0.3
1,888,611 + Rv1664 0.19 -1.6
1,888,642 + Rv1664 0.20 +0.7
1,888,851 + Rv1664 0.27 -0.3
1,888,852 - Rv1664 0.27 -0.1
1,888,852 - Rv1664 0.27 +0.8

Or see this region's nucleotide sequence