Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1488

Experiment: 7H9 with nitrite 5 mM

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with nitrite 5 mM
1,676,420	+		Rv1486c	0.46	-2.0
1,676,421	-		Rv1486c	0.47	-0.3
1,676,421	-		Rv1486c	0.47	+0.4
1,676,762	+		Rv1486c	0.86	+1.1
1,676,896	+				-1.4
1,676,896	+				+1.0
1,676,930	-				-0.2
1,676,935	-				-0.3
1,677,053	+		Rv1487	0.26	+1.7
1,677,204	+		Rv1487	0.60	+0.5
1,677,204	+		Rv1487	0.60	+0.3
1,677,204	+		Rv1487	0.60	-0.1
1,677,205	-		Rv1487	0.61	+0.1
1,677,373	+				-0.4
1,677,374	-				-1.8
1,677,525	+		Rv1488	0.11	-1.8
1,677,525	+		Rv1488	0.11	-0.1
1,677,526	-		Rv1488	0.11	-0.4
1,677,526	-		Rv1488	0.11	-0.5
1,677,676	+		Rv1488	0.24	-0.9
1,677,677	-		Rv1488	0.24	+0.7
1,677,710	-		Rv1488	0.27	+1.2
1,677,724	+		Rv1488	0.29	+0.1
1,677,724	+		Rv1488	0.29	-0.5
1,677,725	-		Rv1488	0.29	-0.3
1,677,725	-		Rv1488	0.29	-0.8
1,677,725	-		Rv1488	0.29	-1.3
1,677,725	-		Rv1488	0.29	-0.3
1,677,988	-		Rv1488	0.52	+0.1
1,677,988	-		Rv1488	0.52	-0.6
1,678,004	+		Rv1488	0.53	+0.4
1,678,004	+		Rv1488	0.53	+0.2
1,678,222	+		Rv1488	0.72	+0.5
1,678,222	+		Rv1488	0.72	-0.1
1,678,228	+		Rv1488	0.73	-0.7
1,678,228	+		Rv1488	0.73	-0.3
1,678,231	-		Rv1488	0.73	-0.6
1,678,275	-		Rv1488	0.77	-0.4
1,678,540	+				+0.5
1,678,541	-				-0.6
1,678,541	-				-0.9
1,678,579	+				+0.3
1,678,579	+				-0.2
1,678,587	-				-0.9
1,678,642	-		Rv1489	0.25	-0.1
1,678,642	-		Rv1489	0.25	-1.2
1,678,642	-		Rv1489	0.25	-0.4
1,678,642	-		Rv1489	0.25	+0.0
1,678,787	-		Rv1489	0.66	+0.1
1,678,837	-		Rv1489	0.80	-1.9
1,678,906	+				+1.6
1,678,906	+				-2.1
1,678,906	+				-0.4
1,678,907	-				+1.5
1,678,907	-				-0.2
1,678,930	+				+1.7
1,678,931	-				-0.4
1,679,190	+				-2.0
1,679,190	+				-0.8
1,679,217	-				-0.3