Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3901c

Experiment: 7H9 with nitrite 2.5 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3899c and Rv3900c overlap by 7 nucleotidesRv3900c and Rv3901c are separated by 56 nucleotidesRv3901c and Rv3902c are separated by 550 nucleotides Rv3899c: Rv3899c - Conserved hypothetical protein, at 4,384,147 to 4,385,379 Rv3899c Rv3900c: Rv3900c - Conserved hypothetical alanine rich protein, at 4,385,373 to 4,386,308 Rv3900c Rv3901c: Rv3901c - Possible membrane protein, at 4,386,365 to 4,386,814 Rv3901c Rv3902c: Rv3902c - Hypothetical protein, at 4,387,365 to 4,387,895 Rv3902c Position (kb) 4386 4387Strain fitness (log2 ratio) -3 -2 -1 0 1 2 3at 4385.409 kb on + strandat 4385.409 kb on + strandat 4385.417 kb on - strandat 4385.495 kb on + strand, within Rv3900cat 4385.532 kb on + strand, within Rv3900cat 4385.533 kb on - strand, within Rv3900cat 4385.533 kb on - strand, within Rv3900cat 4385.568 kb on + strand, within Rv3900cat 4385.808 kb on - strand, within Rv3900cat 4386.229 kb on - strandat 4386.229 kb on - strandat 4386.282 kb on - strandat 4386.282 kb on - strandat 4386.310 kb on + strandat 4386.310 kb on + strandat 4386.310 kb on + strandat 4386.310 kb on + strandat 4386.310 kb on + strandat 4386.310 kb on + strandat 4386.311 kb on - strandat 4386.311 kb on - strandat 4386.311 kb on - strandat 4386.321 kb on + strandat 4386.322 kb on - strandat 4386.391 kb on + strandat 4386.391 kb on + strandat 4386.391 kb on + strandat 4386.392 kb on - strandat 4386.392 kb on - strandat 4386.449 kb on + strand, within Rv3901cat 4386.449 kb on + strand, within Rv3901cat 4386.450 kb on - strand, within Rv3901cat 4386.450 kb on - strand, within Rv3901cat 4386.545 kb on + strand, within Rv3901cat 4386.545 kb on + strand, within Rv3901cat 4386.546 kb on - strand, within Rv3901cat 4386.567 kb on + strand, within Rv3901cat 4386.568 kb on - strand, within Rv3901cat 4386.568 kb on - strand, within Rv3901cat 4386.568 kb on - strand, within Rv3901cat 4386.568 kb on - strand, within Rv3901cat 4386.568 kb on - strand, within Rv3901cat 4386.615 kb on + strand, within Rv3901cat 4386.615 kb on + strand, within Rv3901cat 4386.615 kb on + strand, within Rv3901cat 4386.615 kb on + strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.616 kb on - strand, within Rv3901cat 4386.619 kb on + strand, within Rv3901cat 4386.619 kb on + strand, within Rv3901cat 4386.619 kb on + strand, within Rv3901cat 4386.619 kb on + strand, within Rv3901cat 4386.620 kb on - strand, within Rv3901cat 4386.733 kb on + strand, within Rv3901cat 4386.733 kb on + strand, within Rv3901cat 4386.733 kb on + strand, within Rv3901cat 4386.733 kb on + strand, within Rv3901cat 4386.733 kb on + strand, within Rv3901cat 4386.734 kb on - strand, within Rv3901cat 4386.734 kb on - strand, within Rv3901cat 4386.747 kb on - strand, within Rv3901cat 4386.785 kb on - strandat 4386.785 kb on - strandat 4386.853 kb on + strandat 4386.853 kb on + strandat 4386.854 kb on - strandat 4386.854 kb on - strandat 4386.854 kb on - strandat 4386.854 kb on - strandat 4386.985 kb on + strandat 4386.986 kb on - strandat 4386.986 kb on - strandat 4386.986 kb on - strandat 4387.055 kb on + strandat 4387.055 kb on + strandat 4387.056 kb on - strandat 4387.056 kb on - strandat 4387.056 kb on - strandat 4387.056 kb on - strandat 4387.056 kb on - strandat 4387.056 kb on - strandat 4387.301 kb on + strandat 4387.319 kb on - strandat 4387.322 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 2.5 mM
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4,385,409 + -0.2
4,385,409 + -0.6
4,385,417 - -1.2
4,385,495 + Rv3900c 0.13 -0.1
4,385,532 + Rv3900c 0.17 +0.9
4,385,533 - Rv3900c 0.17 -0.8
4,385,533 - Rv3900c 0.17 -0.9
4,385,568 + Rv3900c 0.21 -0.3
4,385,808 - Rv3900c 0.46 -0.0
4,386,229 - +0.3
4,386,229 - +0.9
4,386,282 - -0.6
4,386,282 - -0.6
4,386,310 + -0.5
4,386,310 + -0.3
4,386,310 + +0.0
4,386,310 + -0.6
4,386,310 + -0.7
4,386,310 + -0.5
4,386,311 - +1.0
4,386,311 - -0.1
4,386,311 - +0.4
4,386,321 + +0.1
4,386,322 - +0.7
4,386,391 + -0.5
4,386,391 + -0.2
4,386,391 + -1.6
4,386,392 - +0.4
4,386,392 - -0.3
4,386,449 + Rv3901c 0.19 -0.9
4,386,449 + Rv3901c 0.19 -2.0
4,386,450 - Rv3901c 0.19 -2.9
4,386,450 - Rv3901c 0.19 -0.6
4,386,545 + Rv3901c 0.40 -2.4
4,386,545 + Rv3901c 0.40 -0.4
4,386,546 - Rv3901c 0.40 +0.2
4,386,567 + Rv3901c 0.45 -1.8
4,386,568 - Rv3901c 0.45 +1.3
4,386,568 - Rv3901c 0.45 +0.1
4,386,568 - Rv3901c 0.45 -2.6
4,386,568 - Rv3901c 0.45 -0.1
4,386,568 - Rv3901c 0.45 -0.8
4,386,615 + Rv3901c 0.56 +0.1
4,386,615 + Rv3901c 0.56 -0.2
4,386,615 + Rv3901c 0.56 -0.4
4,386,615 + Rv3901c 0.56 -0.2
4,386,616 - Rv3901c 0.56 -0.4
4,386,616 - Rv3901c 0.56 -2.3
4,386,616 - Rv3901c 0.56 +3.5
4,386,616 - Rv3901c 0.56 +1.9
4,386,616 - Rv3901c 0.56 +0.8
4,386,616 - Rv3901c 0.56 +0.9
4,386,616 - Rv3901c 0.56 -0.8
4,386,619 + Rv3901c 0.56 -0.5
4,386,619 + Rv3901c 0.56 -1.0
4,386,619 + Rv3901c 0.56 -0.3
4,386,619 + Rv3901c 0.56 -1.1
4,386,620 - Rv3901c 0.57 -0.7
4,386,733 + Rv3901c 0.82 +0.7
4,386,733 + Rv3901c 0.82 -0.8
4,386,733 + Rv3901c 0.82 -0.3
4,386,733 + Rv3901c 0.82 +0.3
4,386,733 + Rv3901c 0.82 +1.5
4,386,734 - Rv3901c 0.82 -0.0
4,386,734 - Rv3901c 0.82 -0.9
4,386,747 - Rv3901c 0.85 -0.1
4,386,785 - -1.2
4,386,785 - -0.5
4,386,853 + -0.2
4,386,853 + -0.0
4,386,854 - -0.0
4,386,854 - +0.3
4,386,854 - -0.1
4,386,854 - -0.0
4,386,985 + -0.5
4,386,986 - -2.0
4,386,986 - +0.1
4,386,986 - -0.2
4,387,055 + -0.2
4,387,055 + +2.3
4,387,056 - +0.3
4,387,056 - +0.1
4,387,056 - -0.4
4,387,056 - +1.3
4,387,056 - -0.8
4,387,056 - -0.8
4,387,301 + -0.6
4,387,319 - -0.2
4,387,322 - -0.2

Or see this region's nucleotide sequence