Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3619c

Experiment: 7H9 with nitrite 2.5 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3618 and Rv3619c are separated by 98 nucleotidesRv3619c and Rv3620c are separated by 26 nucleotidesRv3620c and Rv3621c are separated by 56 nucleotides Rv3618: Rv3618 - Possible monooxygenase, at 4,058,698 to 4,059,885 Rv3618 Rv3619c: Rv3619c - Putative ESAT-6 like protein EsxV (ESAT-6 like protein 1), at 4,059,984 to 4,060,268 Rv3619c Rv3620c: Rv3620c - Putative ESAT-6 like protein EsxW (ESAT-6 like protein 10), at 4,060,295 to 4,060,591 Rv3620c Rv3621c: Rv3621c - PPE family protein PPE65, at 4,060,648 to 4,061,889 Rv3621c Position (kb) 4059 4060 4061Strain fitness (log2 ratio) -2 -1 0 1 2 3at 4059.052 kb on + strand, within Rv3618at 4059.052 kb on + strand, within Rv3618at 4059.053 kb on - strand, within Rv3618at 4059.205 kb on + strand, within Rv3618at 4059.205 kb on + strand, within Rv3618at 4059.323 kb on - strand, within Rv3618at 4059.491 kb on - strand, within Rv3618at 4059.569 kb on - strand, within Rv3618at 4059.712 kb on + strand, within Rv3618at 4059.712 kb on + strand, within Rv3618at 4059.713 kb on - strand, within Rv3618at 4059.713 kb on - strand, within Rv3618at 4059.742 kb on + strand, within Rv3618at 4059.790 kb on - strandat 4059.923 kb on - strandat 4059.923 kb on - strandat 4059.973 kb on + strandat 4059.974 kb on - strandat 4059.974 kb on - strandat 4060.591 kb on + strandat 4060.641 kb on + strandat 4060.641 kb on + strandat 4060.642 kb on - strandat 4060.716 kb on + strandat 4061.031 kb on - strand, within Rv3621cat 4061.031 kb on - strand, within Rv3621c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with nitrite 2.5 mM
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4,059,052 + Rv3618 0.30 -0.5
4,059,052 + Rv3618 0.30 -1.1
4,059,053 - Rv3618 0.30 -0.0
4,059,205 + Rv3618 0.43 +0.5
4,059,205 + Rv3618 0.43 -1.9
4,059,323 - Rv3618 0.53 -0.8
4,059,491 - Rv3618 0.67 +0.3
4,059,569 - Rv3618 0.73 -0.2
4,059,712 + Rv3618 0.85 -1.2
4,059,712 + Rv3618 0.85 -0.8
4,059,713 - Rv3618 0.85 -0.5
4,059,713 - Rv3618 0.85 -0.7
4,059,742 + Rv3618 0.88 +0.2
4,059,790 - -0.3
4,059,923 - -0.3
4,059,923 - -1.7
4,059,973 + -0.0
4,059,974 - +0.9
4,059,974 - -0.1
4,060,591 + +0.4
4,060,641 + -0.3
4,060,641 + -0.6
4,060,642 - -0.8
4,060,716 + -0.2
4,061,031 - Rv3621c 0.31 +3.5
4,061,031 - Rv3621c 0.31 -1.7

Or see this region's nucleotide sequence