Experiment: 7H9 with copper (II) chloride 0.08 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3336c and Rv3337 are separated by 24 nucleotides Rv3337 and Rv3338 overlap by 139 nucleotides Rv3338 and Rv3339c are separated by 66 nucleotides Rv3339c and Rv3340 are separated by 282 nucleotides
Rv3336c: Rv3336c - Probable tryptophanyl-tRNA synthetase TrpS (tryptophan--tRNA ligase) (TRPRS) (tryptophan translase), at 3,722,621 to 3,723,631
Rv3336c
Rv3337: Rv3337 - Conserved hypothetical protein, at 3,723,656 to 3,724,042
Rv3337
Rv3338: Rv3338 - Conserved hypothetical protein, at 3,723,904 to 3,724,548
Rv3338
Rv3339c: Rv3339c - Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP), at 3,724,615 to 3,725,844
Rv3339c
Rv3340: Rv3340 - Probable O-acetylhomoserine sulfhydrylase MetC (homocysteine synthase) (O-acetylhomoserine (thiol)-lyase) (OAH sulfhydrylase) (O-acetyl-L-homoserine sulfhydrylase), at 3,726,127 to 3,727,476
Rv3340
Position (kb)
3724
3725
3726 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 3723.715 kb on + strand, within Rv3337 at 3723.727 kb on + strand, within Rv3337 at 3723.728 kb on - strand, within Rv3337 at 3723.769 kb on - strand, within Rv3337 at 3723.774 kb on + strand, within Rv3337 at 3723.774 kb on + strand, within Rv3337 at 3723.774 kb on + strand, within Rv3337 at 3723.775 kb on - strand, within Rv3337 at 3723.849 kb on + strand, within Rv3337 at 3723.849 kb on + strand, within Rv3337 at 3723.849 kb on + strand, within Rv3337 at 3723.850 kb on - strand, within Rv3337 at 3723.973 kb on - strand at 3723.973 kb on - strand at 3724.105 kb on - strand, within Rv3338 at 3724.277 kb on - strand, within Rv3338 at 3724.547 kb on - strand at 3724.547 kb on - strand at 3724.816 kb on + strand, within Rv3339c at 3724.817 kb on - strand, within Rv3339c at 3724.881 kb on - strand, within Rv3339c at 3724.881 kb on - strand, within Rv3339c at 3724.890 kb on - strand, within Rv3339c at 3724.982 kb on + strand, within Rv3339c at 3724.982 kb on + strand, within Rv3339c at 3725.021 kb on + strand, within Rv3339c at 3725.099 kb on + strand, within Rv3339c at 3725.100 kb on - strand, within Rv3339c at 3725.144 kb on + strand, within Rv3339c at 3725.213 kb on + strand, within Rv3339c at 3725.213 kb on + strand, within Rv3339c at 3725.213 kb on + strand, within Rv3339c at 3725.214 kb on - strand, within Rv3339c at 3725.214 kb on - strand, within Rv3339c at 3725.214 kb on - strand, within Rv3339c at 3725.216 kb on - strand, within Rv3339c at 3725.289 kb on - strand, within Rv3339c at 3725.289 kb on - strand, within Rv3339c at 3725.420 kb on + strand, within Rv3339c at 3725.712 kb on - strand, within Rv3339c at 3725.712 kb on - strand, within Rv3339c at 3725.803 kb on + strand at 3725.824 kb on + strand at 3725.863 kb on - strand at 3725.865 kb on + strand at 3725.866 kb on - strand at 3725.866 kb on - strand at 3725.885 kb on + strand at 3725.944 kb on + strand at 3725.945 kb on - strand at 3725.945 kb on - strand at 3726.058 kb on + strand at 3726.502 kb on + strand, within Rv3340
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with copper (II) chloride 0.08 mM remove 3,723,715 + Rv3337 0.15 -1.3 3,723,727 + Rv3337 0.18 +0.8 3,723,728 - Rv3337 0.19 -0.6 3,723,769 - Rv3337 0.29 -0.1 3,723,774 + Rv3337 0.30 -0.6 3,723,774 + Rv3337 0.30 +0.1 3,723,774 + Rv3337 0.30 -0.4 3,723,775 - Rv3337 0.31 -1.4 3,723,849 + Rv3337 0.50 -1.3 3,723,849 + Rv3337 0.50 +0.5 3,723,849 + Rv3337 0.50 +1.0 3,723,850 - Rv3337 0.50 -0.5 3,723,973 - -0.2 3,723,973 - +1.0 3,724,105 - Rv3338 0.31 -0.3 3,724,277 - Rv3338 0.58 +0.1 3,724,547 - +0.0 3,724,547 - -1.3 3,724,816 + Rv3339c 0.16 +0.5 3,724,817 - Rv3339c 0.16 +0.8 3,724,881 - Rv3339c 0.22 -0.7 3,724,881 - Rv3339c 0.22 -0.1 3,724,890 - Rv3339c 0.22 -1.3 3,724,982 + Rv3339c 0.30 -0.7 3,724,982 + Rv3339c 0.30 -0.3 3,725,021 + Rv3339c 0.33 -2.8 3,725,099 + Rv3339c 0.39 -1.7 3,725,100 - Rv3339c 0.39 -1.3 3,725,144 + Rv3339c 0.43 -0.1 3,725,213 + Rv3339c 0.49 +0.1 3,725,213 + Rv3339c 0.49 +0.7 3,725,213 + Rv3339c 0.49 +0.0 3,725,214 - Rv3339c 0.49 -0.3 3,725,214 - Rv3339c 0.49 -0.4 3,725,214 - Rv3339c 0.49 -1.3 3,725,216 - Rv3339c 0.49 -1.1 3,725,289 - Rv3339c 0.55 -1.2 3,725,289 - Rv3339c 0.55 -1.3 3,725,420 + Rv3339c 0.65 -2.1 3,725,712 - Rv3339c 0.89 -0.6 3,725,712 - Rv3339c 0.89 -0.4 3,725,803 + -0.6 3,725,824 + -1.5 3,725,863 - +0.1 3,725,865 + -1.4 3,725,866 - +0.0 3,725,866 - +1.8 3,725,885 + -0.2 3,725,944 + +0.9 3,725,945 - +0.9 3,725,945 - -0.7 3,726,058 + -1.6 3,726,502 + Rv3340 0.28 -0.8
Or see this region's nucleotide sequence