Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2919c

Experiment: 7H9 with copper (II) chloride 0.08 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2918c and Rv2919c are separated by 57 nucleotidesRv2919c and Rv2920c overlap by 4 nucleotides Rv2918c: Rv2918c - Probable [protein-PII] uridylyltransferase GlnD (PII uridylyl-transferase) (uridylyl removing enzyme) (UTASE), at 3,228,254 to 3,230,680 Rv2918c Rv2919c: Rv2919c - Probable nitrogen regulatory protein P-II GlnB, at 3,230,738 to 3,231,076 Rv2919c Rv2920c: Rv2920c - Probable ammonium-transport integral membrane protein Amt, at 3,231,073 to 3,232,506 Rv2920c Position (kb) 3230 3231 3232Strain fitness (log2 ratio) -2 -1 0 1at 3230.940 kb on + strand, within Rv2919cat 3231.103 kb on + strandat 3231.103 kb on + strandat 3231.104 kb on - strandat 3231.105 kb on + strandat 3231.105 kb on + strandat 3231.106 kb on - strandat 3231.362 kb on + strand, within Rv2920cat 3231.646 kb on - strand, within Rv2920cat 3231.909 kb on + strand, within Rv2920c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with copper (II) chloride 0.08 mM
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3,230,940 + Rv2919c 0.60 -1.4
3,231,103 + +0.2
3,231,103 + -0.7
3,231,104 - -2.1
3,231,105 + +0.3
3,231,105 + -0.1
3,231,106 - +0.2
3,231,362 + Rv2920c 0.20 -0.3
3,231,646 - Rv2920c 0.40 -1.7
3,231,909 + Rv2920c 0.58 +1.7

Or see this region's nucleotide sequence