Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2014

Experiment: 7H9 with copper (II) chloride 0.08 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2013 and Rv2014 overlap by 47 nucleotidesRv2014 and Rv2015c are separated by 127 nucleotides Rv2013: Rv2013 - Transposase, at 2,260,665 to 2,261,144 Rv2013 Rv2014: Rv2014 - Transposase, at 2,261,098 to 2,261,688 Rv2014 Rv2015c: Rv2015c - Conserved hypothetical protein, at 2,261,816 to 2,263,072 Rv2015c Position (kb) 2261 2262Strain fitness (log2 ratio) -2 -1 0 1at 2260.171 kb on + strandat 2260.172 kb on - strandat 2261.269 kb on - strand, within Rv2014at 2261.269 kb on - strand, within Rv2014at 2261.698 kb on - strandat 2261.817 kb on + strandat 2261.817 kb on + strandat 2261.817 kb on + strandat 2261.817 kb on + strandat 2261.856 kb on + strandat 2261.856 kb on + strandat 2261.857 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with copper (II) chloride 0.08 mM
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2,260,171 + -1.6
2,260,172 - -0.1
2,261,269 - Rv2014 0.29 -0.4
2,261,269 - Rv2014 0.29 -2.0
2,261,698 - -0.0
2,261,817 + +0.1
2,261,817 + -0.1
2,261,817 + +1.2
2,261,817 + +1.6
2,261,856 + -0.9
2,261,856 + +0.9
2,261,857 - -0.7

Or see this region's nucleotide sequence