Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1718

Experiment: 7H9 with copper (II) chloride 0.08 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1716 and Rv1717 overlap by 1 nucleotidesRv1717 and Rv1718 are separated by 52 nucleotidesRv1718 and Rv1719 are separated by 13 nucleotidesRv1719 and GFF1787 are separated by 192 nucleotides Rv1716: Rv1716 - Conserved hypothetical protein, at 1,943,576 to 1,944,406 Rv1716 Rv1717: Rv1717 - Conserved hypothetical protein, at 1,944,406 to 1,944,756 Rv1717 Rv1718: Rv1718 - Conserved hypothetical protein, at 1,944,809 to 1,945,627 Rv1718 Rv1719: Rv1719 - Probable transcriptional regulatory protein, at 1,945,641 to 1,946,420 Rv1719 GFF1787 - tRNA-Pro, at 1,946,613 to 1,946,686 GFF1787 Position (kb) 1944 1945 1946Strain fitness (log2 ratio) -2 -1 0 1at 1943.963 kb on + strand, within Rv1716at 1943.964 kb on - strand, within Rv1716at 1943.964 kb on - strand, within Rv1716at 1943.981 kb on + strand, within Rv1716at 1943.985 kb on - strand, within Rv1716at 1943.990 kb on + strand, within Rv1716at 1944.239 kb on + strand, within Rv1716at 1944.239 kb on + strand, within Rv1716at 1944.240 kb on - strand, within Rv1716at 1944.440 kb on - strandat 1944.584 kb on - strand, within Rv1717at 1944.686 kb on + strand, within Rv1717at 1944.917 kb on + strand, within Rv1718at 1944.917 kb on + strand, within Rv1718at 1944.917 kb on + strand, within Rv1718at 1945.235 kb on + strand, within Rv1718at 1945.235 kb on + strand, within Rv1718at 1945.236 kb on - strand, within Rv1718at 1945.415 kb on - strand, within Rv1718at 1945.490 kb on + strand, within Rv1718at 1945.491 kb on - strand, within Rv1718at 1945.533 kb on + strand, within Rv1718at 1945.546 kb on - strandat 1946.502 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with copper (II) chloride 0.08 mM
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1,943,963 + Rv1716 0.47 +1.4
1,943,964 - Rv1716 0.47 -0.1
1,943,964 - Rv1716 0.47 -0.7
1,943,981 + Rv1716 0.49 -1.2
1,943,985 - Rv1716 0.49 -0.4
1,943,990 + Rv1716 0.50 -0.2
1,944,239 + Rv1716 0.80 +0.9
1,944,239 + Rv1716 0.80 -1.5
1,944,240 - Rv1716 0.80 +1.1
1,944,440 - +0.2
1,944,584 - Rv1717 0.51 -2.1
1,944,686 + Rv1717 0.80 +0.0
1,944,917 + Rv1718 0.13 -0.9
1,944,917 + Rv1718 0.13 -0.3
1,944,917 + Rv1718 0.13 +0.5
1,945,235 + Rv1718 0.52 -0.1
1,945,235 + Rv1718 0.52 -0.6
1,945,236 - Rv1718 0.52 -0.0
1,945,415 - Rv1718 0.74 -0.0
1,945,490 + Rv1718 0.83 +0.5
1,945,491 - Rv1718 0.83 +1.3
1,945,533 + Rv1718 0.88 +1.2
1,945,546 - -0.5
1,946,502 - +1.3

Or see this region's nucleotide sequence