Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2286c

Experiment: 7H9 with copper (II) chloride 0.08 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2285 and Rv2286c are separated by 66 nucleotidesRv2286c and Rv2287 are separated by 133 nucleotides Rv2285: Rv2285 - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 2,557,473 to 2,558,810 Rv2285 Rv2286c: Rv2286c - Conserved hypothetical protein, at 2,558,877 to 2,559,569 Rv2286c Rv2287: Rv2287 - Probable conserved integral membrane transport protein YjcE, at 2,559,703 to 2,561,331 Rv2287 Position (kb) 2558 2559 2560Strain fitness (log2 ratio) -2 -1 0 1 2at 2558.127 kb on - strand, within Rv2285at 2558.127 kb on - strand, within Rv2285at 2558.272 kb on - strand, within Rv2285at 2558.498 kb on - strand, within Rv2285at 2558.870 kb on + strandat 2558.954 kb on - strand, within Rv2286cat 2558.961 kb on + strand, within Rv2286cat 2558.961 kb on + strand, within Rv2286cat 2558.962 kb on - strand, within Rv2286cat 2558.962 kb on - strand, within Rv2286cat 2558.962 kb on - strand, within Rv2286cat 2559.016 kb on + strand, within Rv2286cat 2559.017 kb on - strand, within Rv2286cat 2559.017 kb on - strand, within Rv2286cat 2559.325 kb on + strand, within Rv2286cat 2559.326 kb on - strand, within Rv2286cat 2559.394 kb on + strand, within Rv2286cat 2559.395 kb on - strand, within Rv2286cat 2559.703 kb on - strandat 2560.163 kb on + strand, within Rv2287at 2560.164 kb on - strand, within Rv2287at 2560.286 kb on - strand, within Rv2287at 2560.338 kb on - strand, within Rv2287at 2560.471 kb on + strand, within Rv2287at 2560.471 kb on + strand, within Rv2287at 2560.471 kb on + strand, within Rv2287at 2560.472 kb on - strand, within Rv2287at 2560.472 kb on - strand, within Rv2287

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with copper (II) chloride 0.08 mM
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2,558,127 - Rv2285 0.49 -0.2
2,558,127 - Rv2285 0.49 +0.4
2,558,272 - Rv2285 0.60 -0.0
2,558,498 - Rv2285 0.77 -0.5
2,558,870 + -0.2
2,558,954 - Rv2286c 0.11 -0.0
2,558,961 + Rv2286c 0.12 -0.7
2,558,961 + Rv2286c 0.12 -0.3
2,558,962 - Rv2286c 0.12 -1.4
2,558,962 - Rv2286c 0.12 -1.8
2,558,962 - Rv2286c 0.12 -0.9
2,559,016 + Rv2286c 0.20 +0.1
2,559,017 - Rv2286c 0.20 +1.8
2,559,017 - Rv2286c 0.20 -1.6
2,559,325 + Rv2286c 0.65 -0.2
2,559,326 - Rv2286c 0.65 -2.1
2,559,394 + Rv2286c 0.75 -1.2
2,559,395 - Rv2286c 0.75 -0.5
2,559,703 - -1.1
2,560,163 + Rv2287 0.28 -0.3
2,560,164 - Rv2287 0.28 -0.4
2,560,286 - Rv2287 0.36 +0.4
2,560,338 - Rv2287 0.39 +0.8
2,560,471 + Rv2287 0.47 -1.0
2,560,471 + Rv2287 0.47 -0.3
2,560,471 + Rv2287 0.47 -1.9
2,560,472 - Rv2287 0.47 +1.2
2,560,472 - Rv2287 0.47 -0.9

Or see this region's nucleotide sequence