Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0784

Experiment: 7H9 with Norfloxacin 0.125 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0783c and Rv0784 are separated by 197 nucleotidesRv0784 and Rv0785 are separated by 15 nucleotides Rv0783c: Rv0783c - Possible multidrug resistance integral membrane efflux protein EmrB, at 876,818 to 878,440 Rv0783c Rv0784: Rv0784 - Conserved hypothetical protein, at 878,638 to 879,324 Rv0784 Rv0785: Rv0785 - Conserved protein, at 879,340 to 881,040 Rv0785 Position (kb) 878 879 880Strain fitness (log2 ratio) -1 0 1at 877.691 kb on - strand, within Rv0783cat 878.034 kb on - strand, within Rv0783cat 878.560 kb on + strandat 878.836 kb on + strand, within Rv0784at 879.432 kb on - strandat 879.592 kb on - strand, within Rv0785at 879.653 kb on - strand, within Rv0785at 879.680 kb on - strand, within Rv0785at 879.680 kb on - strand, within Rv0785at 880.233 kb on + strand, within Rv0785at 880.233 kb on + strand, within Rv0785at 880.234 kb on - strand, within Rv0785at 880.241 kb on - strand, within Rv0785

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Norfloxacin 0.125 mM
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877,691 - Rv0783c 0.54 -0.5
878,034 - Rv0783c 0.75 -0.8
878,560 + -0.3
878,836 + Rv0784 0.29 +0.5
879,432 - -0.1
879,592 - Rv0785 0.15 -0.5
879,653 - Rv0785 0.18 +0.2
879,680 - Rv0785 0.20 -0.1
879,680 - Rv0785 0.20 +0.6
880,233 + Rv0785 0.52 -1.4
880,233 + Rv0785 0.52 -0.7
880,234 - Rv0785 0.53 -0.6
880,241 - Rv0785 0.53 -0.9

Or see this region's nucleotide sequence