Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2259

Experiment: 7H9 with Formaldehyde 0.23 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2258c and Rv2259 are separated by 347 nucleotidesRv2259 and Rv2260 overlap by 1 nucleotidesRv2260 and Rv2261c are separated by 76 nucleotides Rv2258c: Rv2258c - Possible transcriptional regulatory protein, at 2,530,836 to 2,531,897 Rv2258c Rv2259: Rv2259 - S-nitrosomycothiol reductase MscR, at 2,532,245 to 2,533,330 Rv2259 Rv2260: Rv2260 - Conserved hypothetical protein, at 2,533,330 to 2,533,965 Rv2260 Rv2261c: Rv2261c - Conserved hypothetical protein, at 2,534,042 to 2,534,464 Rv2261c Position (kb) 2532 2533 2534Strain fitness (log2 ratio) -4 -3 -2 -1 0 1 2at 2531.503 kb on + strand, within Rv2258cat 2531.581 kb on - strand, within Rv2258cat 2531.717 kb on - strand, within Rv2258cat 2532.225 kb on + strandat 2532.232 kb on + strandat 2532.232 kb on + strandat 2532.233 kb on - strandat 2532.233 kb on - strandat 2532.374 kb on - strand, within Rv2259at 2532.386 kb on + strand, within Rv2259at 2532.413 kb on + strand, within Rv2259at 2532.413 kb on + strand, within Rv2259at 2532.451 kb on - strand, within Rv2259at 2532.472 kb on - strand, within Rv2259at 2533.209 kb on - strand, within Rv2259at 2533.305 kb on + strandat 2533.305 kb on + strandat 2533.306 kb on - strandat 2533.868 kb on + strand, within Rv2260at 2534.011 kb on + strandat 2534.012 kb on - strandat 2534.243 kb on - strand, within Rv2261c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Formaldehyde 0.23 mM
remove
2,531,503 + Rv2258c 0.63 -0.3
2,531,581 - Rv2258c 0.70 +0.2
2,531,717 - Rv2258c 0.83 +0.1
2,532,225 + +0.0
2,532,232 + +0.4
2,532,232 + +2.6
2,532,233 - -1.5
2,532,233 - +1.8
2,532,374 - Rv2259 0.12 -2.0
2,532,386 + Rv2259 0.13 -1.4
2,532,413 + Rv2259 0.15 -3.7
2,532,413 + Rv2259 0.15 +0.5
2,532,451 - Rv2259 0.19 -4.3
2,532,472 - Rv2259 0.21 -3.6
2,533,209 - Rv2259 0.89 -3.2
2,533,305 + -3.2
2,533,305 + -2.5
2,533,306 - -3.1
2,533,868 + Rv2260 0.85 -0.9
2,534,011 + -0.2
2,534,012 - -1.4
2,534,243 - Rv2261c 0.48 -0.5

Or see this region's nucleotide sequence