Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0727c

Experiment: 7H9 with Formaldehyde 0.23 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0726c and Rv0727c are separated by 202 nucleotidesRv0727c and Rv0728c overlap by 4 nucleotides Rv0726c: Rv0726c - Possible S-adenosylmethionine-dependent methyltransferase, at 818,537 to 819,640 Rv0726c Rv0727c: Rv0727c - Possible L-fuculose phosphate aldolase FucA (L-fuculose-1-phosphate aldolase), at 819,843 to 820,499 Rv0727c Rv0728c: Rv0728c - Possible D-3-phosphoglycerate dehydrogenase SerA2 (phosphoglycerate dehydrogenase) (PGDH), at 820,496 to 821,476 Rv0728c Position (kb) 819 820 821Strain fitness (log2 ratio) -2 -1 0 1at 818.862 kb on + strand, within Rv0726cat 818.970 kb on - strand, within Rv0726cat 819.055 kb on - strand, within Rv0726cat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.633 kb on + strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.634 kb on - strandat 819.680 kb on - strandat 819.680 kb on - strandat 819.752 kb on + strandat 819.792 kb on - strandat 819.792 kb on - strandat 819.844 kb on + strandat 819.872 kb on - strandat 820.102 kb on + strand, within Rv0727cat 820.132 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.257 kb on + strand, within Rv0727cat 820.258 kb on - strand, within Rv0727cat 820.263 kb on + strand, within Rv0727cat 820.264 kb on - strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.323 kb on + strand, within Rv0727cat 820.355 kb on - strand, within Rv0727cat 820.508 kb on + strandat 820.508 kb on + strandat 820.509 kb on - strandat 821.356 kb on - strand, within Rv0728cat 821.391 kb on + strandat 821.393 kb on + strandat 821.393 kb on + strandat 821.394 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Formaldehyde 0.23 mM
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818,862 + Rv0726c 0.29 -0.1
818,970 - Rv0726c 0.39 +0.4
819,055 - Rv0726c 0.47 -0.4
819,633 + -0.1
819,633 + +0.3
819,633 + +0.3
819,633 + -0.2
819,633 + +0.2
819,633 + -0.4
819,633 + -0.0
819,633 + -0.0
819,634 - +0.1
819,634 - -0.2
819,634 - +0.7
819,634 - -0.4
819,634 - +1.0
819,634 - -2.3
819,634 - -0.1
819,634 - +0.4
819,680 - -0.5
819,680 - -0.9
819,752 + -2.2
819,792 - -0.7
819,792 - -0.8
819,844 + -0.2
819,872 - -2.2
820,102 + Rv0727c 0.39 +0.3
820,132 + Rv0727c 0.44 -0.2
820,257 + Rv0727c 0.63 -0.8
820,257 + Rv0727c 0.63 -1.1
820,257 + Rv0727c 0.63 +0.9
820,257 + Rv0727c 0.63 +0.7
820,258 - Rv0727c 0.63 +0.3
820,263 + Rv0727c 0.64 -0.3
820,264 - Rv0727c 0.64 +0.1
820,323 + Rv0727c 0.73 +0.2
820,323 + Rv0727c 0.73 +0.5
820,323 + Rv0727c 0.73 +1.2
820,323 + Rv0727c 0.73 +1.7
820,355 - Rv0727c 0.78 +0.2
820,508 + -0.1
820,508 + -1.4
820,509 - +0.2
821,356 - Rv0728c 0.88 -0.6
821,391 + -0.2
821,393 + -0.2
821,393 + -0.0
821,394 - -1.0

Or see this region's nucleotide sequence