Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0418

Experiment: 7H9 with Formaldehyde 0.23 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0417 and Rv0418 are separated by 371 nucleotidesRv0418 and Rv0419 are separated by 87 nucleotides Rv0417: Rv0417 - Probable thiamin biosynthesis protein ThiG (thiazole biosynthesis protein), at 502,366 to 503,124 Rv0417 Rv0418: Rv0418 - Probable lipoprotein aminopeptidase LpqL, at 503,496 to 504,998 Rv0418 Rv0419: Rv0419 - Possible lipoprotein peptidase LpqM, at 505,086 to 506,582 Rv0419 Position (kb) 503 504 505Strain fitness (log2 ratio) -1 0 1 2at 503.198 kb on + strandat 503.199 kb on - strandat 503.211 kb on + strandat 503.287 kb on + strandat 503.302 kb on + strandat 503.378 kb on + strandat 503.401 kb on - strandat 503.582 kb on + strandat 503.582 kb on + strandat 504.128 kb on + strand, within Rv0418at 504.132 kb on - strand, within Rv0418at 504.565 kb on - strand, within Rv0418at 504.834 kb on + strand, within Rv0418at 504.835 kb on - strand, within Rv0418at 504.866 kb on - strandat 504.906 kb on + strandat 504.906 kb on + strandat 504.921 kb on + strandat 505.389 kb on + strand, within Rv0419at 505.404 kb on + strand, within Rv0419at 505.475 kb on + strand, within Rv0419at 505.476 kb on - strand, within Rv0419at 505.503 kb on + strand, within Rv0419at 505.503 kb on + strand, within Rv0419at 505.504 kb on - strand, within Rv0419at 505.588 kb on - strand, within Rv0419at 505.664 kb on + strand, within Rv0419at 505.722 kb on + strand, within Rv0419at 505.745 kb on + strand, within Rv0419at 505.745 kb on + strand, within Rv0419at 505.760 kb on + strand, within Rv0419at 505.761 kb on - strand, within Rv0419

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Formaldehyde 0.23 mM
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503,198 + +0.3
503,199 - +0.4
503,211 + -0.9
503,287 + -0.5
503,302 + +0.5
503,378 + -0.2
503,401 - -0.9
503,582 + -0.9
503,582 + -0.0
504,128 + Rv0418 0.42 -1.2
504,132 - Rv0418 0.42 -0.6
504,565 - Rv0418 0.71 -0.4
504,834 + Rv0418 0.89 -1.6
504,835 - Rv0418 0.89 -0.2
504,866 - +0.7
504,906 + -1.3
504,906 + -0.5
504,921 + -0.0
505,389 + Rv0419 0.20 +0.3
505,404 + Rv0419 0.21 -0.2
505,475 + Rv0419 0.26 +0.2
505,476 - Rv0419 0.26 +1.6
505,503 + Rv0419 0.28 -0.4
505,503 + Rv0419 0.28 -0.1
505,504 - Rv0419 0.28 +0.2
505,588 - Rv0419 0.34 -0.2
505,664 + Rv0419 0.39 +2.6
505,722 + Rv0419 0.42 -0.4
505,745 + Rv0419 0.44 -0.7
505,745 + Rv0419 0.44 +1.2
505,760 + Rv0419 0.45 -0.2
505,761 - Rv0419 0.45 -0.1

Or see this region's nucleotide sequence