Experiment: 7H9 with methylglyoxal 1.2 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3672c and Rv3673c are separated by 131 nucleotides Rv3673c and Rv3674c overlap by 1 nucleotides Rv3674c and Rv3675 are separated by 107 nucleotides Rv3675 and Rv3676 are separated by 98 nucleotides
Rv3672c: Rv3672c - Conserved hypothetical protein, at 4,113,521 to 4,114,342
Rv3672c
Rv3673c: Rv3673c - Possible membrane-anchored thioredoxin-like protein (thiol-disulfide interchange related protein), at 4,114,474 to 4,115,157
Rv3673c
Rv3674c: Rv3674c - Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)), at 4,115,157 to 4,115,894
Rv3674c
Rv3675: Rv3675 - Possible membrane protein, at 4,116,002 to 4,116,379
Rv3675
Rv3676: Rv3676 - Transcriptional regulatory protein Crp (Crp/Fnr-family), at 4,116,478 to 4,117,152
Rv3676
Position (kb)
4115
4116 Strain fitness (log2 ratio)
-1
0
1
2 at 4114.218 kb on - strand, within Rv3672c at 4114.471 kb on + strand at 4115.158 kb on + strand at 4115.159 kb on - strand at 4115.575 kb on - strand, within Rv3674c at 4115.575 kb on - strand, within Rv3674c at 4115.575 kb on - strand, within Rv3674c at 4115.671 kb on + strand, within Rv3674c at 4115.672 kb on - strand, within Rv3674c at 4115.751 kb on + strand, within Rv3674c at 4115.802 kb on + strand, within Rv3674c at 4115.803 kb on - strand, within Rv3674c at 4115.957 kb on + strand at 4115.958 kb on - strand at 4116.007 kb on + strand at 4116.008 kb on - strand at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.304 kb on + strand, within Rv3675 at 4116.405 kb on + strand at 4116.447 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with methylglyoxal 1.2 mM remove 4,114,218 - Rv3672c 0.85 +0.8 4,114,471 + -0.6 4,115,158 + -0.6 4,115,159 - -0.2 4,115,575 - Rv3674c 0.57 +2.4 4,115,575 - Rv3674c 0.57 -0.5 4,115,575 - Rv3674c 0.57 +0.0 4,115,671 + Rv3674c 0.70 -0.4 4,115,672 - Rv3674c 0.70 -0.1 4,115,751 + Rv3674c 0.80 -0.4 4,115,802 + Rv3674c 0.87 -0.6 4,115,803 - Rv3674c 0.88 +0.4 4,115,957 + -1.4 4,115,958 - +0.1 4,116,007 + -1.4 4,116,008 - +0.2 4,116,167 - Rv3675 0.44 -0.4 4,116,167 - Rv3675 0.44 -1.5 4,116,167 - Rv3675 0.44 +0.0 4,116,167 - Rv3675 0.44 +0.5 4,116,304 + Rv3675 0.80 -0.4 4,116,405 + +0.2 4,116,447 + -0.2
Or see this region's nucleotide sequence