Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1276c

Experiment: 7H9 with methylglyoxal 1.2 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1274 and Rv1275 overlap by 4 nucleotidesRv1275 and Rv1276c are separated by 144 nucleotidesRv1276c and Rv1277 are separated by 249 nucleotides Rv1274: Rv1274 - Possible lipoprotein LprB, at 1,424,197 to 1,424,754 Rv1274 Rv1275: Rv1275 - Possible lipoprotein LprC, at 1,424,751 to 1,425,293 Rv1275 Rv1276c: Rv1276c - Conserved hypothetical protein, at 1,425,438 to 1,425,914 Rv1276c Rv1277: Rv1277 - Conserved hypothetical protein, at 1,426,164 to 1,427,417 Rv1277 Position (kb) 1425 1426Strain fitness (log2 ratio) -1 0 1at 1425.336 kb on + strandat 1425.336 kb on + strandat 1425.344 kb on + strandat 1425.357 kb on - strandat 1425.404 kb on + strandat 1425.511 kb on - strand, within Rv1276cat 1425.715 kb on + strand, within Rv1276cat 1425.931 kb on + strandat 1425.957 kb on - strandat 1426.085 kb on + strandat 1426.085 kb on + strandat 1426.086 kb on - strandat 1426.089 kb on + strandat 1426.089 kb on + strandat 1426.090 kb on - strandat 1426.090 kb on - strandat 1426.090 kb on - strandat 1426.222 kb on + strandat 1426.223 kb on - strandat 1426.223 kb on - strandat 1426.223 kb on - strandat 1426.375 kb on + strand, within Rv1277at 1426.414 kb on + strand, within Rv1277at 1426.459 kb on + strand, within Rv1277at 1426.506 kb on + strand, within Rv1277at 1426.840 kb on - strand, within Rv1277at 1426.868 kb on + strand, within Rv1277

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with methylglyoxal 1.2 mM
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1,425,336 + +1.2
1,425,336 + -0.1
1,425,344 + -0.5
1,425,357 - +0.4
1,425,404 + -0.0
1,425,511 - Rv1276c 0.15 +1.4
1,425,715 + Rv1276c 0.58 +0.2
1,425,931 + -0.4
1,425,957 - -0.6
1,426,085 + +0.4
1,426,085 + -0.3
1,426,086 - -0.2
1,426,089 + -0.2
1,426,089 + +0.0
1,426,090 - -1.4
1,426,090 - +1.2
1,426,090 - -0.5
1,426,222 + -0.5
1,426,223 - -0.0
1,426,223 - +0.5
1,426,223 - -0.2
1,426,375 + Rv1277 0.17 -0.8
1,426,414 + Rv1277 0.20 -0.7
1,426,459 + Rv1277 0.24 -1.2
1,426,506 + Rv1277 0.27 -0.9
1,426,840 - Rv1277 0.54 -0.5
1,426,868 + Rv1277 0.56 +0.7

Or see this region's nucleotide sequence