Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1732c

Experiment: 7H9 with Ramoplanin 0.009 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1731 and Rv1732c are separated by 9 nucleotidesRv1732c and Rv1733c are separated by 63 nucleotidesRv1733c and Rv1734c are separated by 286 nucleotides Rv1731: Rv1731 - Possible succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD2, at 1,957,677 to 1,959,233 Rv1731 Rv1732c: Rv1732c - Conserved protein, at 1,959,243 to 1,959,791 Rv1732c Rv1733c: Rv1733c - Probable conserved transmembrane protein, at 1,959,855 to 1,960,487 Rv1733c Rv1734c: Rv1734c - Conserved hypothetical protein, at 1,960,774 to 1,961,016 Rv1734c Position (kb) 1959 1960Strain fitness (log2 ratio) -2 -1 0 1 2at 1958.269 kb on - strand, within Rv1731at 1958.356 kb on - strand, within Rv1731at 1958.559 kb on + strand, within Rv1731at 1958.559 kb on + strand, within Rv1731at 1958.661 kb on - strand, within Rv1731at 1958.860 kb on - strand, within Rv1731at 1959.007 kb on - strand, within Rv1731at 1959.191 kb on - strandat 1959.479 kb on - strand, within Rv1732cat 1959.484 kb on + strand, within Rv1732cat 1959.647 kb on - strand, within Rv1732cat 1959.803 kb on + strandat 1959.804 kb on - strandat 1960.605 kb on - strandat 1960.715 kb on + strandat 1960.716 kb on - strandat 1960.716 kb on - strandat 1960.719 kb on + strandat 1960.735 kb on + strandat 1960.735 kb on + strandat 1960.783 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ramoplanin 0.009 mM
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1,958,269 - Rv1731 0.38 -0.6
1,958,356 - Rv1731 0.44 +0.9
1,958,559 + Rv1731 0.57 +0.3
1,958,559 + Rv1731 0.57 -0.1
1,958,661 - Rv1731 0.63 +0.4
1,958,860 - Rv1731 0.76 -0.3
1,959,007 - Rv1731 0.85 +2.1
1,959,191 - -0.6
1,959,479 - Rv1732c 0.43 -0.8
1,959,484 + Rv1732c 0.44 -1.1
1,959,647 - Rv1732c 0.74 -0.5
1,959,803 + -0.0
1,959,804 - +0.6
1,960,605 - -0.7
1,960,715 + -0.9
1,960,716 - +2.1
1,960,716 - +0.4
1,960,719 + -1.8
1,960,735 + -0.1
1,960,735 + +1.7
1,960,783 + -0.8

Or see this region's nucleotide sequence