Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3409c and Rv3410c are separated by 55 nucleotides Rv3410c and Rv3411c are separated by 19 nucleotides
Rv3409c: Rv3409c - Cholesterol oxidase ChoD (cholesterol-O2 oxidoreductase), at 3,826,991 to 3,828,727
Rv3409c
Rv3410c: Rv3410c - Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD), at 3,828,783 to 3,829,910
Rv3410c
Rv3411c: Rv3411c - Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase) (imp oxidoreductase) (inosine-5'-monophosphate oxidoreductase) (IMPDH) (IMPD), at 3,829,930 to 3,831,519
Rv3411c
Position (kb)
3828
3829
3830 Strain fitness (log2 ratio)
-2
-1
0
1 at 3827.882 kb on - strand, within Rv3409c at 3828.369 kb on + strand, within Rv3409c at 3828.370 kb on - strand, within Rv3409c at 3828.447 kb on + strand, within Rv3409c at 3828.448 kb on - strand, within Rv3409c at 3828.448 kb on - strand, within Rv3409c at 3828.526 kb on + strand, within Rv3409c at 3828.526 kb on + strand, within Rv3409c at 3828.527 kb on - strand, within Rv3409c at 3828.714 kb on + strand at 3828.736 kb on + strand at 3828.736 kb on + strand at 3828.737 kb on - strand at 3828.737 kb on - strand at 3828.748 kb on + strand at 3828.749 kb on - strand at 3828.749 kb on - strand at 3828.749 kb on - strand at 3828.749 kb on - strand at 3828.763 kb on - strand at 3829.941 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM remove 3,827,882 - Rv3409c 0.51 -0.1 3,828,369 + Rv3409c 0.79 -0.3 3,828,370 - Rv3409c 0.79 -1.3 3,828,447 + Rv3409c 0.84 -0.4 3,828,448 - Rv3409c 0.84 +0.7 3,828,448 - Rv3409c 0.84 -0.2 3,828,526 + Rv3409c 0.88 -2.1 3,828,526 + Rv3409c 0.88 -1.0 3,828,527 - Rv3409c 0.88 -0.9 3,828,714 + -0.5 3,828,736 + -0.5 3,828,736 + +0.1 3,828,737 - -0.8 3,828,737 - -1.6 3,828,748 + -0.9 3,828,749 - -0.5 3,828,749 - -0.2 3,828,749 - +0.2 3,828,749 - +0.1 3,828,763 - +0.2 3,829,941 - +0.1
Or see this region's nucleotide sequence