Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0400c and Rv0401 are separated by 35 nucleotides Rv0401 and Rv0402c are separated by 194 nucleotides Rv0402c and Rv0403c overlap by 4 nucleotides Rv0403c and Rv0404 are separated by 320 nucleotides
Rv0400c: Rv0400c - Acyl-CoA dehydrogenase FadE7, at 478,566 to 479,753
Rv0400c
Rv0401: Rv0401 - Probable conserved transmembrane protein, at 479,789 to 480,160
Rv0401
Rv0402c: Rv0402c - Probable conserved transmembrane transport protein MmpL1, at 480,355 to 483,231
Rv0402c
Rv0403c: Rv0403c - Probable conserved membrane protein MmpS1, at 483,228 to 483,656
Rv0403c
Rv0404: Rv0404 - Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase), at 483,977 to 485,734
Rv0404
Position (kb) 480
481
482
483
484 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 479.497 kb on + strand, within Rv0400c at 479.498 kb on - strand, within Rv0400c at 479.498 kb on - strand, within Rv0400c at 479.498 kb on - strand, within Rv0400c at 479.761 kb on + strand at 480.314 kb on + strand at 480.336 kb on + strand at 480.498 kb on - strand at 480.704 kb on - strand, within Rv0402c at 480.783 kb on + strand, within Rv0402c at 480.783 kb on + strand, within Rv0402c at 480.947 kb on + strand, within Rv0402c at 480.947 kb on + strand, within Rv0402c at 480.947 kb on + strand, within Rv0402c at 480.948 kb on - strand, within Rv0402c at 480.948 kb on - strand, within Rv0402c at 480.975 kb on - strand, within Rv0402c at 480.998 kb on + strand, within Rv0402c at 481.367 kb on - strand, within Rv0402c at 481.512 kb on - strand, within Rv0402c at 481.600 kb on - strand, within Rv0402c at 481.611 kb on + strand, within Rv0402c at 481.611 kb on + strand, within Rv0402c at 481.611 kb on + strand, within Rv0402c at 481.612 kb on - strand, within Rv0402c at 481.612 kb on - strand, within Rv0402c at 481.612 kb on - strand, within Rv0402c at 482.009 kb on + strand, within Rv0402c at 482.009 kb on + strand, within Rv0402c at 482.010 kb on - strand, within Rv0402c at 482.010 kb on - strand, within Rv0402c at 482.013 kb on - strand, within Rv0402c at 482.013 kb on - strand, within Rv0402c at 482.024 kb on + strand, within Rv0402c at 482.025 kb on - strand, within Rv0402c at 482.036 kb on + strand, within Rv0402c at 482.036 kb on + strand, within Rv0402c at 482.069 kb on - strand, within Rv0402c at 482.301 kb on - strand, within Rv0402c at 482.366 kb on + strand, within Rv0402c at 482.436 kb on - strand, within Rv0402c at 482.487 kb on + strand, within Rv0402c at 482.488 kb on - strand, within Rv0402c at 482.597 kb on + strand, within Rv0402c at 482.671 kb on + strand, within Rv0402c at 482.672 kb on - strand, within Rv0402c at 482.711 kb on + strand, within Rv0402c at 482.711 kb on + strand, within Rv0402c at 482.822 kb on + strand, within Rv0402c at 482.823 kb on - strand, within Rv0402c at 482.823 kb on - strand, within Rv0402c at 482.939 kb on + strand, within Rv0402c at 483.073 kb on + strand at 483.135 kb on + strand at 483.387 kb on - strand, within Rv0403c at 483.387 kb on - strand, within Rv0403c at 483.446 kb on - strand, within Rv0403c at 483.488 kb on - strand, within Rv0403c at 483.615 kb on + strand at 483.615 kb on + strand at 483.616 kb on - strand at 483.616 kb on - strand at 483.616 kb on - strand at 483.815 kb on + strand at 483.987 kb on + strand at 484.199 kb on + strand, within Rv0404 at 484.199 kb on + strand, within Rv0404
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM remove 479,497 + Rv0400c 0.78 -0.7 479,498 - Rv0400c 0.78 -0.3 479,498 - Rv0400c 0.78 -0.6 479,498 - Rv0400c 0.78 -0.8 479,761 + +0.4 480,314 + -0.4 480,336 + -2.1 480,498 - -0.6 480,704 - Rv0402c 0.12 +0.3 480,783 + Rv0402c 0.15 -1.1 480,783 + Rv0402c 0.15 +0.4 480,947 + Rv0402c 0.21 +1.1 480,947 + Rv0402c 0.21 +1.2 480,947 + Rv0402c 0.21 +0.6 480,948 - Rv0402c 0.21 -0.5 480,948 - Rv0402c 0.21 -0.1 480,975 - Rv0402c 0.22 +0.3 480,998 + Rv0402c 0.22 -0.2 481,367 - Rv0402c 0.35 -2.1 481,512 - Rv0402c 0.40 +3.6 481,600 - Rv0402c 0.43 +1.8 481,611 + Rv0402c 0.44 -0.3 481,611 + Rv0402c 0.44 +1.0 481,611 + Rv0402c 0.44 -0.6 481,612 - Rv0402c 0.44 -1.5 481,612 - Rv0402c 0.44 -0.5 481,612 - Rv0402c 0.44 +1.3 482,009 + Rv0402c 0.57 -0.7 482,009 + Rv0402c 0.57 +0.0 482,010 - Rv0402c 0.58 +0.4 482,010 - Rv0402c 0.58 +0.1 482,013 - Rv0402c 0.58 -0.3 482,013 - Rv0402c 0.58 +0.1 482,024 + Rv0402c 0.58 -0.3 482,025 - Rv0402c 0.58 -0.4 482,036 + Rv0402c 0.58 -1.4 482,036 + Rv0402c 0.58 -0.5 482,069 - Rv0402c 0.60 -1.4 482,301 - Rv0402c 0.68 -0.2 482,366 + Rv0402c 0.70 -0.3 482,436 - Rv0402c 0.72 -0.1 482,487 + Rv0402c 0.74 -1.4 482,488 - Rv0402c 0.74 +0.6 482,597 + Rv0402c 0.78 +0.3 482,671 + Rv0402c 0.81 -0.0 482,672 - Rv0402c 0.81 -0.1 482,711 + Rv0402c 0.82 +0.0 482,711 + Rv0402c 0.82 -0.4 482,822 + Rv0402c 0.86 +0.3 482,823 - Rv0402c 0.86 -0.4 482,823 - Rv0402c 0.86 -0.1 482,939 + Rv0402c 0.90 +0.8 483,073 + -0.4 483,135 + +0.1 483,387 - Rv0403c 0.37 -0.1 483,387 - Rv0403c 0.37 -0.8 483,446 - Rv0403c 0.51 -0.1 483,488 - Rv0403c 0.61 -0.5 483,615 + -0.7 483,615 + +0.5 483,616 - -1.2 483,616 - -0.5 483,616 - -0.2 483,815 + +2.6 483,987 + -1.4 484,199 + Rv0404 0.13 -0.6 484,199 + Rv0404 0.13 -0.2
Or see this region's nucleotide sequence