Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3895c

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3894c and Rv3895c are separated by 0 nucleotidesRv3895c and Rv3896c are separated by 2 nucleotides Rv3894c: Rv3894c - ESX conserved component EccC2. ESX-2 type VII secretion system protein. Possible membrane protein., at 4,376,262 to 4,380,452 Rv3894c Rv3895c: Rv3895c - ESX conserved component EccB2. ESX-2 type VII secretion system protein. Probable membrane protein., at 4,380,453 to 4,381,940 Rv3895c Rv3896c: Rv3896c - Conserved hypothetical protein, at 4,381,943 to 4,382,851 Rv3896c Position (kb) 4380 4381 4382Strain fitness (log2 ratio) -1 0 1 2at 4379.549 kb on + strand, within Rv3894cat 4379.983 kb on - strand, within Rv3894cat 4379.983 kb on - strand, within Rv3894cat 4380.140 kb on - strandat 4380.280 kb on + strandat 4380.280 kb on + strandat 4380.281 kb on - strandat 4380.454 kb on + strandat 4380.454 kb on + strandat 4380.798 kb on + strand, within Rv3895cat 4380.856 kb on + strand, within Rv3895cat 4381.040 kb on - strand, within Rv3895cat 4381.040 kb on - strand, within Rv3895cat 4381.112 kb on - strand, within Rv3895cat 4381.361 kb on - strand, within Rv3895cat 4381.361 kb on - strand, within Rv3895cat 4381.690 kb on + strand, within Rv3895cat 4381.891 kb on + strandat 4382.037 kb on + strand, within Rv3896cat 4382.037 kb on + strand, within Rv3896cat 4382.037 kb on + strand, within Rv3896cat 4382.103 kb on + strand, within Rv3896cat 4382.183 kb on + strand, within Rv3896cat 4382.199 kb on + strand, within Rv3896cat 4382.334 kb on - strand, within Rv3896cat 4382.334 kb on - strand, within Rv3896cat 4382.413 kb on + strand, within Rv3896cat 4382.413 kb on + strand, within Rv3896cat 4382.653 kb on - strand, within Rv3896cat 4382.653 kb on - strand, within Rv3896cat 4382.937 kb on + strandat 4382.937 kb on + strandat 4382.937 kb on + strandat 4382.938 kb on - strandat 4382.938 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
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4,379,549 + Rv3894c 0.78 +0.5
4,379,983 - Rv3894c 0.89 -0.9
4,379,983 - Rv3894c 0.89 -0.9
4,380,140 - -0.1
4,380,280 + -0.4
4,380,280 + -0.9
4,380,281 - +0.3
4,380,454 + +0.1
4,380,454 + -0.3
4,380,798 + Rv3895c 0.23 +0.9
4,380,856 + Rv3895c 0.27 +1.6
4,381,040 - Rv3895c 0.39 +0.7
4,381,040 - Rv3895c 0.39 +0.7
4,381,112 - Rv3895c 0.44 +0.6
4,381,361 - Rv3895c 0.61 +1.5
4,381,361 - Rv3895c 0.61 -0.5
4,381,690 + Rv3895c 0.83 -0.1
4,381,891 + +0.8
4,382,037 + Rv3896c 0.10 -0.6
4,382,037 + Rv3896c 0.10 -0.1
4,382,037 + Rv3896c 0.10 +1.0
4,382,103 + Rv3896c 0.18 +2.5
4,382,183 + Rv3896c 0.26 -1.1
4,382,199 + Rv3896c 0.28 -1.2
4,382,334 - Rv3896c 0.43 +0.3
4,382,334 - Rv3896c 0.43 -0.4
4,382,413 + Rv3896c 0.52 +0.3
4,382,413 + Rv3896c 0.52 -1.0
4,382,653 - Rv3896c 0.78 -1.3
4,382,653 - Rv3896c 0.78 +1.5
4,382,937 + -0.4
4,382,937 + +2.5
4,382,937 + +0.1
4,382,938 - +0.8
4,382,938 - -0.1

Or see this region's nucleotide sequence