Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3831

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv3829c and Rv3830c are separated by 47 nucleotidesRv3830c and Rv3831 are separated by 71 nucleotidesRv3831 and Rv3832c overlap by 4 nucleotidesRv3832c and Rv3833 are separated by 55 nucleotides Rv3829c: Rv3829c - Probable dehydrogenase, at 4,303,398 to 4,305,008 Rv3829c Rv3830c: Rv3830c - Transcriptional regulatory protein (probably TetR-family), at 4,305,056 to 4,305,685 Rv3830c Rv3831: Rv3831 - Hypothetical protein, at 4,305,757 to 4,306,239 Rv3831 Rv3832c: Rv3832c - Conserved protein, at 4,306,236 to 4,306,811 Rv3832c Rv3833: Rv3833 - Transcriptional regulatory protein (probably AraC-family), at 4,306,867 to 4,307,658 Rv3833 Position (kb) 4305 4306 4307Strain fitness (log2 ratio) -2 -1 0 1 2 3at 4304.906 kb on + strandat 4304.907 kb on - strandat 4304.907 kb on - strandat 4304.989 kb on - strandat 4305.008 kb on + strandat 4305.323 kb on - strand, within Rv3830cat 4305.376 kb on - strand, within Rv3830cat 4305.537 kb on + strand, within Rv3830cat 4305.880 kb on + strand, within Rv3831at 4305.881 kb on - strand, within Rv3831at 4305.883 kb on + strand, within Rv3831at 4305.883 kb on + strand, within Rv3831at 4305.883 kb on + strand, within Rv3831at 4305.884 kb on - strand, within Rv3831at 4305.884 kb on - strand, within Rv3831at 4305.997 kb on + strand, within Rv3831at 4306.048 kb on + strand, within Rv3831at 4306.048 kb on + strand, within Rv3831at 4306.048 kb on + strand, within Rv3831at 4306.049 kb on - strand, within Rv3831at 4306.049 kb on - strand, within Rv3831at 4306.130 kb on - strand, within Rv3831at 4306.177 kb on + strand, within Rv3831at 4306.298 kb on + strand, within Rv3832cat 4306.299 kb on - strand, within Rv3832cat 4306.299 kb on - strand, within Rv3832cat 4306.358 kb on - strand, within Rv3832cat 4306.358 kb on - strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.374 kb on + strand, within Rv3832cat 4306.375 kb on - strand, within Rv3832cat 4306.375 kb on - strand, within Rv3832cat 4306.375 kb on - strand, within Rv3832cat 4306.377 kb on + strand, within Rv3832cat 4306.459 kb on - strand, within Rv3832cat 4306.794 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.824 kb on + strandat 4306.825 kb on - strandat 4306.825 kb on - strandat 4306.825 kb on - strandat 4306.828 kb on + strandat 4306.863 kb on + strandat 4307.099 kb on + strand, within Rv3833

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
remove
4,304,906 + +0.4
4,304,907 - +0.1
4,304,907 - -0.2
4,304,989 - -0.0
4,305,008 + +2.0
4,305,323 - Rv3830c 0.42 +0.8
4,305,376 - Rv3830c 0.51 -0.3
4,305,537 + Rv3830c 0.76 -0.4
4,305,880 + Rv3831 0.25 +1.4
4,305,881 - Rv3831 0.26 -0.5
4,305,883 + Rv3831 0.26 -0.5
4,305,883 + Rv3831 0.26 -1.0
4,305,883 + Rv3831 0.26 -0.3
4,305,884 - Rv3831 0.26 +3.1
4,305,884 - Rv3831 0.26 -0.0
4,305,997 + Rv3831 0.50 -1.8
4,306,048 + Rv3831 0.60 +0.2
4,306,048 + Rv3831 0.60 -0.2
4,306,048 + Rv3831 0.60 +1.0
4,306,049 - Rv3831 0.60 -0.5
4,306,049 - Rv3831 0.60 +0.6
4,306,130 - Rv3831 0.77 -0.5
4,306,177 + Rv3831 0.87 +1.2
4,306,298 + Rv3832c 0.11 +0.3
4,306,299 - Rv3832c 0.11 -0.2
4,306,299 - Rv3832c 0.11 -0.1
4,306,358 - Rv3832c 0.21 +0.2
4,306,358 - Rv3832c 0.21 -0.2
4,306,374 + Rv3832c 0.24 +0.1
4,306,374 + Rv3832c 0.24 +0.2
4,306,374 + Rv3832c 0.24 -1.0
4,306,374 + Rv3832c 0.24 -0.0
4,306,374 + Rv3832c 0.24 -0.4
4,306,375 - Rv3832c 0.24 -0.5
4,306,375 - Rv3832c 0.24 -0.0
4,306,375 - Rv3832c 0.24 +2.1
4,306,377 + Rv3832c 0.24 +0.9
4,306,459 - Rv3832c 0.39 +0.2
4,306,794 + -1.0
4,306,824 + +0.1
4,306,824 + +0.6
4,306,824 + -0.0
4,306,824 + -0.5
4,306,824 + +0.5
4,306,824 + +0.5
4,306,825 - -0.3
4,306,825 - -0.3
4,306,825 - -0.0
4,306,828 + -0.3
4,306,863 + +0.0
4,307,099 + Rv3833 0.29 -0.7

Or see this region's nucleotide sequence