Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3014c and Rv3015c are separated by 30 nucleotides Rv3015c and Rv3016 are separated by 93 nucleotides Rv3016 and Rv3017c are separated by 102 nucleotides
Rv3014c: Rv3014c - DNA ligase [NAD dependent] LigA (polydeoxyribonucleotide synthase [NAD+]), at 3,372,545 to 3,374,620
Rv3014c
Rv3015c: Rv3015c - Conserved hypothetical protein, at 3,374,651 to 3,375,664
Rv3015c
Rv3016: Rv3016 - Probable lipoprotein LpqA, at 3,375,758 to 3,376,387
Rv3016
Rv3017c: Rv3017c - ESAT-6 like protein EsxQ (TB12.9) (ESAT-6 like protein 8), at 3,376,490 to 3,376,852
Rv3017c
Position (kb)
3374
3375
3376 Strain fitness (log2 ratio)
-1
0
1
2 at 3374.778 kb on - strand, within Rv3015c at 3375.400 kb on + strand, within Rv3015c at 3375.400 kb on + strand, within Rv3015c at 3375.561 kb on + strand, within Rv3015c at 3375.676 kb on - strand at 3375.786 kb on + strand at 3375.787 kb on - strand at 3375.787 kb on - strand at 3375.801 kb on + strand at 3375.802 kb on - strand at 3375.886 kb on + strand, within Rv3016 at 3375.971 kb on + strand, within Rv3016 at 3375.972 kb on - strand, within Rv3016 at 3375.972 kb on - strand, within Rv3016 at 3376.006 kb on - strand, within Rv3016 at 3376.225 kb on + strand, within Rv3016 at 3376.251 kb on + strand, within Rv3016 at 3376.251 kb on + strand, within Rv3016 at 3376.251 kb on + strand, within Rv3016 at 3376.283 kb on + strand, within Rv3016 at 3376.386 kb on - strand at 3376.626 kb on - strand, within Rv3017c at 3376.648 kb on - strand, within Rv3017c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM remove 3,374,778 - Rv3015c 0.13 -0.0 3,375,400 + Rv3015c 0.74 -0.3 3,375,400 + Rv3015c 0.74 -1.4 3,375,561 + Rv3015c 0.90 -1.4 3,375,676 - -0.8 3,375,786 + +0.7 3,375,787 - +0.2 3,375,787 - +0.3 3,375,801 + -0.1 3,375,802 - -1.2 3,375,886 + Rv3016 0.20 -0.5 3,375,971 + Rv3016 0.34 -0.7 3,375,972 - Rv3016 0.34 +1.8 3,375,972 - Rv3016 0.34 -0.9 3,376,006 - Rv3016 0.39 +1.1 3,376,225 + Rv3016 0.74 -0.7 3,376,251 + Rv3016 0.78 +1.1 3,376,251 + Rv3016 0.78 -0.7 3,376,251 + Rv3016 0.78 +1.8 3,376,283 + Rv3016 0.83 -0.5 3,376,386 - -0.6 3,376,626 - Rv3017c 0.37 +1.8 3,376,648 - Rv3017c 0.44 -0.5
Or see this region's nucleotide sequence