Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2314c

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2313c and Rv2314c are separated by 10 nucleotidesRv2314c and Rv2315c overlap by 4 nucleotides Rv2313c: Rv2313c - Hypothetical protein, at 2,585,052 to 2,585,906 Rv2313c Rv2314c: Rv2314c - Conserved protein, at 2,585,917 to 2,587,290 Rv2314c Rv2315c: Rv2315c - Conserved protein, at 2,587,287 to 2,588,804 Rv2315c Position (kb) 2585 2586 2587 2588Strain fitness (log2 ratio) -1 0 1 2 3 4at 2584.948 kb on + strandat 2585.000 kb on + strandat 2585.014 kb on + strandat 2585.015 kb on - strandat 2585.016 kb on + strandat 2585.016 kb on + strandat 2585.016 kb on + strandat 2585.016 kb on + strandat 2585.017 kb on - strandat 2585.017 kb on - strandat 2585.090 kb on - strandat 2585.259 kb on + strand, within Rv2313cat 2585.260 kb on - strand, within Rv2313cat 2585.338 kb on + strand, within Rv2313cat 2585.338 kb on + strand, within Rv2313cat 2585.338 kb on + strand, within Rv2313cat 2585.557 kb on + strand, within Rv2313cat 2585.557 kb on + strand, within Rv2313cat 2585.557 kb on + strand, within Rv2313cat 2585.557 kb on + strand, within Rv2313cat 2585.558 kb on - strand, within Rv2313cat 2585.621 kb on - strand, within Rv2313cat 2585.621 kb on - strand, within Rv2313cat 2585.621 kb on - strand, within Rv2313cat 2585.979 kb on + strandat 2586.122 kb on + strand, within Rv2314cat 2586.123 kb on - strand, within Rv2314cat 2586.861 kb on - strand, within Rv2314cat 2586.861 kb on - strand, within Rv2314cat 2586.861 kb on - strand, within Rv2314cat 2586.861 kb on - strand, within Rv2314cat 2587.098 kb on + strand, within Rv2314cat 2587.099 kb on - strand, within Rv2314cat 2587.099 kb on - strand, within Rv2314cat 2587.202 kb on + strandat 2587.311 kb on - strandat 2587.555 kb on + strand, within Rv2315cat 2587.595 kb on + strand, within Rv2315cat 2587.597 kb on + strand, within Rv2315cat 2587.598 kb on - strand, within Rv2315c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
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2,584,948 + -0.1
2,585,000 + -0.5
2,585,014 + +0.2
2,585,015 - -0.3
2,585,016 + -0.1
2,585,016 + -0.2
2,585,016 + -0.3
2,585,016 + +0.1
2,585,017 - -0.5
2,585,017 - -0.2
2,585,090 - +0.1
2,585,259 + Rv2313c 0.24 +0.3
2,585,260 - Rv2313c 0.24 -0.7
2,585,338 + Rv2313c 0.33 +0.8
2,585,338 + Rv2313c 0.33 +4.0
2,585,338 + Rv2313c 0.33 +1.8
2,585,557 + Rv2313c 0.59 +0.2
2,585,557 + Rv2313c 0.59 +0.0
2,585,557 + Rv2313c 0.59 +0.0
2,585,557 + Rv2313c 0.59 +0.1
2,585,558 - Rv2313c 0.59 +0.0
2,585,621 - Rv2313c 0.67 -0.6
2,585,621 - Rv2313c 0.67 -0.4
2,585,621 - Rv2313c 0.67 -0.5
2,585,979 + -0.3
2,586,122 + Rv2314c 0.15 -0.3
2,586,123 - Rv2314c 0.15 +0.9
2,586,861 - Rv2314c 0.69 -0.1
2,586,861 - Rv2314c 0.69 -1.0
2,586,861 - Rv2314c 0.69 -1.1
2,586,861 - Rv2314c 0.69 -0.1
2,587,098 + Rv2314c 0.86 -0.5
2,587,099 - Rv2314c 0.86 -1.0
2,587,099 - Rv2314c 0.86 -1.2
2,587,202 + -0.2
2,587,311 - +1.6
2,587,555 + Rv2315c 0.18 -1.0
2,587,595 + Rv2315c 0.20 +1.8
2,587,597 + Rv2315c 0.20 -0.5
2,587,598 - Rv2315c 0.20 +0.5

Or see this region's nucleotide sequence