Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1524

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1523 and Rv1524 are separated by 29 nucleotidesRv1524 and Rv1525 are separated by 46 nucleotidesRv1525 and Rv1526c overlap by 23 nucleotides Rv1523: Rv1523 - Probable methyltransferase, at 1,717,653 to 1,718,696 Rv1523 Rv1524: Rv1524 - Probable glycosyltransferase, at 1,718,726 to 1,719,970 Rv1524 Rv1525: Rv1525 - Possible rhamnosyl transferase WbbL2, at 1,720,017 to 1,720,802 Rv1525 Rv1526c: Rv1526c - Probable glycosyltransferase, at 1,720,780 to 1,722,060 Rv1526c Position (kb) 1718 1719 1720Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1717.804 kb on + strand, within Rv1523at 1717.804 kb on + strand, within Rv1523at 1717.920 kb on - strand, within Rv1523at 1717.920 kb on - strand, within Rv1523at 1717.920 kb on - strand, within Rv1523at 1717.924 kb on - strand, within Rv1523at 1717.968 kb on + strand, within Rv1523at 1717.968 kb on + strand, within Rv1523at 1718.086 kb on - strand, within Rv1523at 1718.101 kb on - strand, within Rv1523at 1718.146 kb on + strand, within Rv1523at 1718.147 kb on - strand, within Rv1523at 1718.147 kb on - strand, within Rv1523at 1718.181 kb on + strand, within Rv1523at 1718.211 kb on + strand, within Rv1523at 1718.211 kb on + strand, within Rv1523at 1718.593 kb on + strandat 1718.593 kb on + strandat 1718.676 kb on + strandat 1718.677 kb on - strandat 1718.748 kb on - strandat 1718.748 kb on - strandat 1718.883 kb on - strand, within Rv1524at 1719.065 kb on + strand, within Rv1524at 1719.218 kb on + strand, within Rv1524at 1719.309 kb on + strand, within Rv1524

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
remove
1,717,804 + Rv1523 0.14 +0.3
1,717,804 + Rv1523 0.14 -1.6
1,717,920 - Rv1523 0.26 -0.1
1,717,920 - Rv1523 0.26 -0.5
1,717,920 - Rv1523 0.26 -0.4
1,717,924 - Rv1523 0.26 -0.1
1,717,968 + Rv1523 0.30 +1.9
1,717,968 + Rv1523 0.30 +2.9
1,718,086 - Rv1523 0.41 -1.0
1,718,101 - Rv1523 0.43 -0.2
1,718,146 + Rv1523 0.47 -0.3
1,718,147 - Rv1523 0.47 -0.4
1,718,147 - Rv1523 0.47 -0.9
1,718,181 + Rv1523 0.51 -0.5
1,718,211 + Rv1523 0.53 -0.2
1,718,211 + Rv1523 0.53 +0.1
1,718,593 + -1.0
1,718,593 + +0.9
1,718,676 + +0.5
1,718,677 - -1.9
1,718,748 - -0.2
1,718,748 - -0.9
1,718,883 - Rv1524 0.13 -0.3
1,719,065 + Rv1524 0.27 -0.9
1,719,218 + Rv1524 0.40 -0.7
1,719,309 + Rv1524 0.47 -1.5

Or see this region's nucleotide sequence