Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1277 and Rv1278 overlap by 4 nucleotides Rv1278 and Rv1279 are separated by 20 nucleotides
Rv1277: Rv1277 - Conserved hypothetical protein, at 1,426,164 to 1,427,417
Rv1277
Rv1278: Rv1278 - Hypothetical protein, at 1,427,414 to 1,430,041
Rv1278
Rv1279: Rv1279 - Probable dehydrogenase FAD flavoprotein GMC oxidoreductase, at 1,430,062 to 1,431,648
Rv1279
Position (kb)
1427
1428
1429
1430
1431 Strain fitness (log2 ratio)
-3
-2
-1
0
1 at 1426.414 kb on + strand, within Rv1277 at 1426.459 kb on + strand, within Rv1277 at 1426.506 kb on + strand, within Rv1277 at 1426.840 kb on - strand, within Rv1277 at 1426.868 kb on + strand, within Rv1277 at 1426.960 kb on + strand, within Rv1277 at 1427.039 kb on + strand, within Rv1277 at 1427.255 kb on - strand, within Rv1277 at 1427.562 kb on - strand at 1427.954 kb on + strand, within Rv1278 at 1428.133 kb on - strand, within Rv1278 at 1428.133 kb on - strand, within Rv1278 at 1428.591 kb on + strand, within Rv1278 at 1428.591 kb on + strand, within Rv1278 at 1428.591 kb on + strand, within Rv1278 at 1428.592 kb on - strand, within Rv1278 at 1429.206 kb on + strand, within Rv1278 at 1429.778 kb on + strand, within Rv1278 at 1430.034 kb on + strand at 1430.034 kb on + strand at 1430.035 kb on - strand at 1430.081 kb on - strand at 1430.081 kb on - strand at 1430.081 kb on - strand at 1430.081 kb on - strand at 1430.248 kb on + strand, within Rv1279 at 1430.407 kb on + strand, within Rv1279 at 1431.026 kb on - strand, within Rv1279 at 1431.029 kb on + strand, within Rv1279 at 1431.030 kb on - strand, within Rv1279 at 1431.030 kb on - strand, within Rv1279 at 1431.030 kb on - strand, within Rv1279
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM remove 1,426,414 + Rv1277 0.20 -1.1 1,426,459 + Rv1277 0.24 -3.1 1,426,506 + Rv1277 0.27 -1.5 1,426,840 - Rv1277 0.54 -1.2 1,426,868 + Rv1277 0.56 -0.2 1,426,960 + Rv1277 0.63 +0.8 1,427,039 + Rv1277 0.70 -1.2 1,427,255 - Rv1277 0.87 -1.6 1,427,562 - -2.0 1,427,954 + Rv1278 0.21 -3.6 1,428,133 - Rv1278 0.27 -0.2 1,428,133 - Rv1278 0.27 +0.8 1,428,591 + Rv1278 0.45 -2.3 1,428,591 + Rv1278 0.45 -1.6 1,428,591 + Rv1278 0.45 +0.5 1,428,592 - Rv1278 0.45 -0.7 1,429,206 + Rv1278 0.68 +0.7 1,429,778 + Rv1278 0.90 -0.6 1,430,034 + -1.0 1,430,034 + -0.9 1,430,035 - -1.9 1,430,081 - -1.3 1,430,081 - -1.2 1,430,081 - +0.5 1,430,081 - -0.3 1,430,248 + Rv1279 0.12 -0.2 1,430,407 + Rv1279 0.22 +0.3 1,431,026 - Rv1279 0.61 -0.2 1,431,029 + Rv1279 0.61 +0.5 1,431,030 - Rv1279 0.61 -1.2 1,431,030 - Rv1279 0.61 -0.7 1,431,030 - Rv1279 0.61 -0.1
Or see this region's nucleotide sequence