Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1082 and Rv1083 overlap by 4 nucleotides Rv1083 and Rv1084 overlap by 14 nucleotides Rv1084 and Rv1085c are separated by 98 nucleotides Rv1085c and Rv1086 are separated by 110 nucleotides
Rv1082: Rv1082 - Mycothiol conjugate amidase Mca (mycothiol S-conjugate amidase), at 1,206,520 to 1,207,386
Rv1082
Rv1083: Rv1083 - Conserved hypothetical protein, at 1,207,383 to 1,207,649
Rv1083
Rv1084: Rv1084 - Conserved protein, at 1,207,636 to 1,209,657
Rv1084
Rv1085c: Rv1085c - Possible hemolysin-like protein, at 1,209,756 to 1,210,484
Rv1085c
Rv1086: Rv1086 - Short (C15) chain Z-isoprenyl diphosphate synthase (Z-FPP synthase) (Z-farnesyl diphosphate synthase) (Z-FPP synthetase) (Z-farnesyl diphosphate synthetase) (geranyltranstransferase) (farnesyl pyrophosphate synthetase), at 1,210,595 to 1,211,383
Rv1086
Position (kb)
1207
1208
1209
1210 Strain fitness (log2 ratio)
-2
-1
0
1 at 1206.789 kb on - strand, within Rv1082 at 1206.792 kb on + strand, within Rv1082 at 1206.793 kb on - strand, within Rv1082 at 1206.803 kb on + strand, within Rv1082 at 1206.910 kb on + strand, within Rv1082 at 1207.042 kb on + strand, within Rv1082 at 1207.042 kb on + strand, within Rv1082 at 1207.045 kb on + strand, within Rv1082 at 1207.046 kb on - strand, within Rv1082 at 1207.335 kb on + strand at 1207.648 kb on - strand at 1207.691 kb on - strand at 1207.710 kb on + strand at 1207.927 kb on + strand, within Rv1084 at 1207.928 kb on - strand, within Rv1084 at 1207.928 kb on - strand, within Rv1084 at 1208.021 kb on - strand, within Rv1084 at 1208.282 kb on + strand, within Rv1084 at 1208.294 kb on - strand, within Rv1084 at 1208.369 kb on - strand, within Rv1084 at 1208.369 kb on - strand, within Rv1084 at 1208.446 kb on + strand, within Rv1084 at 1208.630 kb on - strand, within Rv1084 at 1208.630 kb on - strand, within Rv1084 at 1209.073 kb on + strand, within Rv1084 at 1209.577 kb on + strand at 1209.577 kb on + strand at 1209.577 kb on + strand at 1209.578 kb on - strand at 1209.581 kb on + strand at 1209.867 kb on + strand, within Rv1085c at 1209.874 kb on + strand, within Rv1085c at 1209.875 kb on - strand, within Rv1085c at 1209.964 kb on + strand, within Rv1085c at 1209.994 kb on + strand, within Rv1085c at 1209.995 kb on - strand, within Rv1085c at 1210.133 kb on - strand, within Rv1085c at 1210.133 kb on - strand, within Rv1085c at 1210.133 kb on - strand, within Rv1085c at 1210.222 kb on + strand, within Rv1085c at 1210.264 kb on + strand, within Rv1085c at 1210.358 kb on - strand, within Rv1085c at 1210.535 kb on + strand at 1210.581 kb on + strand at 1210.581 kb on + strand at 1210.581 kb on + strand at 1210.582 kb on - strand at 1210.640 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM remove 1,206,789 - Rv1082 0.31 +1.3 1,206,792 + Rv1082 0.31 +0.0 1,206,793 - Rv1082 0.31 -0.5 1,206,803 + Rv1082 0.33 +0.3 1,206,910 + Rv1082 0.45 -0.2 1,207,042 + Rv1082 0.60 +0.2 1,207,042 + Rv1082 0.60 -0.5 1,207,045 + Rv1082 0.61 -0.2 1,207,046 - Rv1082 0.61 -0.8 1,207,335 + +0.2 1,207,648 - -0.1 1,207,691 - -0.2 1,207,710 + +1.2 1,207,927 + Rv1084 0.14 +0.0 1,207,928 - Rv1084 0.14 +0.8 1,207,928 - Rv1084 0.14 +0.3 1,208,021 - Rv1084 0.19 +0.2 1,208,282 + Rv1084 0.32 +0.1 1,208,294 - Rv1084 0.33 -0.6 1,208,369 - Rv1084 0.36 -0.0 1,208,369 - Rv1084 0.36 +0.2 1,208,446 + Rv1084 0.40 +0.8 1,208,630 - Rv1084 0.49 +0.2 1,208,630 - Rv1084 0.49 +0.4 1,209,073 + Rv1084 0.71 +0.7 1,209,577 + +0.6 1,209,577 + -0.5 1,209,577 + +1.3 1,209,578 - -0.5 1,209,581 + +0.7 1,209,867 + Rv1085c 0.15 +0.2 1,209,874 + Rv1085c 0.16 +0.3 1,209,875 - Rv1085c 0.16 +0.8 1,209,964 + Rv1085c 0.29 +0.4 1,209,994 + Rv1085c 0.33 -0.3 1,209,995 - Rv1085c 0.33 +0.8 1,210,133 - Rv1085c 0.52 +0.0 1,210,133 - Rv1085c 0.52 -0.4 1,210,133 - Rv1085c 0.52 +1.2 1,210,222 + Rv1085c 0.64 +0.1 1,210,264 + Rv1085c 0.70 +0.4 1,210,358 - Rv1085c 0.83 +1.1 1,210,535 + +1.2 1,210,581 + -0.4 1,210,581 + +0.2 1,210,581 + -1.2 1,210,582 - +0.4 1,210,640 + -1.8
Or see this region's nucleotide sequence