Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1051c

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1050 and Rv1051c are separated by 158 nucleotides Rv1050: Rv1050 - Probable oxidoreductase, at 1,172,881 to 1,173,786 Rv1050 Rv1051c: Rv1051c - Conserved hypothetical protein, at 1,173,945 to 1,174,700 Rv1051c Position (kb) 1173 1174 1175Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1173.415 kb on - strand, within Rv1050at 1173.710 kb on + strandat 1173.770 kb on - strandat 1174.544 kb on + strand, within Rv1051cat 1174.840 kb on + strandat 1174.841 kb on - strandat 1174.951 kb on + strandat 1174.951 kb on + strandat 1174.952 kb on - strandat 1175.086 kb on - strandat 1175.112 kb on + strandat 1175.113 kb on - strandat 1175.113 kb on - strandat 1175.166 kb on + strandat 1175.167 kb on - strandat 1175.312 kb on - strandat 1175.379 kb on + strandat 1175.379 kb on + strandat 1175.379 kb on + strandat 1175.525 kb on + strandat 1175.525 kb on + strandat 1175.526 kb on - strandat 1175.531 kb on + strandat 1175.531 kb on + strandat 1175.531 kb on + strandat 1175.532 kb on - strandat 1175.538 kb on - strandat 1175.548 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
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1,173,415 - Rv1050 0.59 -0.0
1,173,710 + +0.3
1,173,770 - +1.3
1,174,544 + Rv1051c 0.79 -1.1
1,174,840 + +0.1
1,174,841 - +0.5
1,174,951 + +1.0
1,174,951 + -1.9
1,174,952 - +0.4
1,175,086 - -1.6
1,175,112 + +0.1
1,175,113 - -0.4
1,175,113 - -0.3
1,175,166 + +1.8
1,175,167 - -0.4
1,175,312 - -0.4
1,175,379 + -0.5
1,175,379 + +0.1
1,175,379 + -1.1
1,175,525 + -0.9
1,175,525 + -0.7
1,175,526 - -0.3
1,175,531 + +0.2
1,175,531 + +0.6
1,175,531 + -0.1
1,175,532 - +3.3
1,175,538 - +0.8
1,175,548 + +0.0

Or see this region's nucleotide sequence