Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0297 and Rv0298 are separated by 142 nucleotides Rv0298 and Rv0299 overlap by 4 nucleotides Rv0299 and Rv0300 are separated by 47 nucleotides Rv0300 and Rv0301 overlap by 4 nucleotides
Rv0297: Rv0297 - PE-PGRS family protein PE_PGRS5, at 361,334 to 363,109
Rv0297
Rv0298: Rv0298 - Hypothetical protein, at 363,252 to 363,479
Rv0298
Rv0299: Rv0299 - Hypothetical protein, at 363,476 to 363,778
Rv0299
Rv0300: Rv0300 - Possible antitoxin VapB2, at 363,826 to 364,047
Rv0300
Rv0301: Rv0301 - Possible toxin VapC2, at 364,044 to 364,469
Rv0301
Position (kb) 363
364 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 362.742 kb on + strand, within Rv0297 at 362.742 kb on + strand, within Rv0297 at 362.743 kb on - strand, within Rv0297 at 362.743 kb on - strand, within Rv0297 at 362.743 kb on - strand, within Rv0297 at 362.743 kb on - strand, within Rv0297 at 362.746 kb on + strand, within Rv0297 at 362.747 kb on - strand, within Rv0297 at 362.820 kb on + strand, within Rv0297 at 362.936 kb on - strand at 363.130 kb on + strand at 363.130 kb on + strand at 363.131 kb on - strand at 363.134 kb on + strand at 363.135 kb on - strand at 363.135 kb on - strand at 363.135 kb on - strand at 363.135 kb on - strand at 363.169 kb on + strand at 363.169 kb on + strand at 363.230 kb on + strand at 363.230 kb on + strand at 363.231 kb on - strand at 363.231 kb on - strand at 363.236 kb on + strand at 363.240 kb on - strand at 363.396 kb on + strand, within Rv0298 at 363.404 kb on + strand, within Rv0298 at 363.436 kb on - strand, within Rv0298 at 363.450 kb on + strand, within Rv0298 at 363.527 kb on + strand, within Rv0299 at 363.814 kb on + strand at 363.815 kb on - strand at 363.836 kb on + strand at 363.837 kb on - strand at 363.837 kb on - strand at 363.866 kb on + strand, within Rv0300 at 363.866 kb on + strand, within Rv0300 at 363.867 kb on - strand, within Rv0300 at 364.027 kb on - strand at 364.144 kb on + strand, within Rv0301 at 364.145 kb on - strand, within Rv0301 at 364.145 kb on - strand, within Rv0301 at 364.145 kb on - strand, within Rv0301 at 364.174 kb on + strand, within Rv0301 at 364.175 kb on - strand, within Rv0301 at 364.175 kb on - strand, within Rv0301 at 364.251 kb on + strand, within Rv0301 at 364.251 kb on + strand, within Rv0301 at 364.252 kb on - strand, within Rv0301 at 364.252 kb on - strand, within Rv0301 at 364.252 kb on - strand, within Rv0301 at 364.256 kb on - strand, within Rv0301 at 364.256 kb on - strand, within Rv0301 at 364.256 kb on - strand, within Rv0301 at 364.381 kb on + strand, within Rv0301 at 364.382 kb on - strand, within Rv0301 at 364.382 kb on - strand, within Rv0301
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM remove 362,742 + Rv0297 0.79 -1.5 362,742 + Rv0297 0.79 +1.8 362,743 - Rv0297 0.79 +0.1 362,743 - Rv0297 0.79 -0.5 362,743 - Rv0297 0.79 +2.3 362,743 - Rv0297 0.79 -0.3 362,746 + Rv0297 0.80 -1.0 362,747 - Rv0297 0.80 -0.4 362,820 + Rv0297 0.84 +1.5 362,936 - +0.5 363,130 + -0.2 363,130 + -1.4 363,131 - -0.8 363,134 + +0.4 363,135 - -0.3 363,135 - +0.8 363,135 - +0.0 363,135 - +0.6 363,169 + -0.1 363,169 + -0.3 363,230 + -0.2 363,230 + +0.1 363,231 - -0.6 363,231 - -0.1 363,236 + -0.2 363,240 - +2.7 363,396 + Rv0298 0.63 +0.2 363,404 + Rv0298 0.67 -0.3 363,436 - Rv0298 0.81 +1.4 363,450 + Rv0298 0.87 +0.3 363,527 + Rv0299 0.17 -1.8 363,814 + -1.0 363,815 - -0.0 363,836 + +0.6 363,837 - +0.0 363,837 - +0.0 363,866 + Rv0300 0.18 -1.9 363,866 + Rv0300 0.18 +0.1 363,867 - Rv0300 0.18 -0.5 364,027 - -3.1 364,144 + Rv0301 0.23 -0.4 364,145 - Rv0301 0.24 -0.0 364,145 - Rv0301 0.24 -0.2 364,145 - Rv0301 0.24 -0.1 364,174 + Rv0301 0.31 -0.3 364,175 - Rv0301 0.31 +0.4 364,175 - Rv0301 0.31 +0.2 364,251 + Rv0301 0.49 +1.1 364,251 + Rv0301 0.49 -0.4 364,252 - Rv0301 0.49 +0.2 364,252 - Rv0301 0.49 +0.1 364,252 - Rv0301 0.49 +0.9 364,256 - Rv0301 0.50 +0.1 364,256 - Rv0301 0.50 -0.3 364,256 - Rv0301 0.50 +0.0 364,381 + Rv0301 0.79 -0.1 364,382 - Rv0301 0.79 -0.5 364,382 - Rv0301 0.79 +0.2
Or see this region's nucleotide sequence