Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0213c

Experiment: 7H9 with Ciprofloxacin Hydrochloride 0.001 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0212c and Rv0213c overlap by 4 nucleotidesRv0213c and Rv0214 are separated by 113 nucleotides Rv0212c: Rv0212c - Possible transcriptional regulatory protein NadR (probably AsnC-family), at 253,669 to 254,640 Rv0212c Rv0213c: Rv0213c - Possible methyltransferase (methylase), at 254,637 to 255,950 Rv0213c Rv0214: Rv0214 - Probable fatty-acid-CoA ligase FadD4 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 256,064 to 257,677 Rv0214 Position (kb) 254 255 256Strain fitness (log2 ratio) -2 -1 0 1at 253.891 kb on + strand, within Rv0212cat 253.892 kb on - strand, within Rv0212cat 253.892 kb on - strand, within Rv0212cat 254.051 kb on - strand, within Rv0212cat 254.334 kb on - strand, within Rv0212cat 254.585 kb on + strandat 254.755 kb on - strandat 254.854 kb on + strand, within Rv0213cat 254.854 kb on + strand, within Rv0213cat 254.854 kb on + strand, within Rv0213cat 254.854 kb on + strand, within Rv0213cat 254.910 kb on - strand, within Rv0213cat 254.910 kb on - strand, within Rv0213cat 254.911 kb on + strand, within Rv0213cat 254.978 kb on + strand, within Rv0213cat 254.978 kb on + strand, within Rv0213cat 254.979 kb on - strand, within Rv0213cat 255.089 kb on - strand, within Rv0213cat 255.272 kb on + strand, within Rv0213cat 255.273 kb on - strand, within Rv0213cat 255.295 kb on - strand, within Rv0213cat 255.311 kb on - strand, within Rv0213cat 255.381 kb on + strand, within Rv0213cat 255.381 kb on + strand, within Rv0213cat 255.429 kb on - strand, within Rv0213cat 255.573 kb on + strand, within Rv0213cat 255.573 kb on + strand, within Rv0213cat 255.697 kb on + strand, within Rv0213cat 255.697 kb on + strand, within Rv0213cat 255.697 kb on + strand, within Rv0213cat 255.831 kb on + strandat 255.982 kb on + strandat 255.982 kb on + strandat 256.018 kb on + strandat 256.019 kb on - strandat 256.019 kb on - strandat 256.082 kb on + strandat 256.176 kb on - strandat 256.176 kb on - strandat 256.209 kb on - strandat 256.209 kb on - strandat 256.376 kb on + strand, within Rv0214at 256.377 kb on - strand, within Rv0214at 256.380 kb on - strand, within Rv0214at 256.421 kb on + strand, within Rv0214at 256.421 kb on + strand, within Rv0214at 256.422 kb on - strand, within Rv0214at 256.635 kb on - strand, within Rv0214at 256.755 kb on + strand, within Rv0214at 256.756 kb on - strand, within Rv0214at 256.757 kb on + strand, within Rv0214at 256.758 kb on - strand, within Rv0214at 256.779 kb on - strand, within Rv0214

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ciprofloxacin Hydrochloride 0.001 mM
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253,891 + Rv0212c 0.23 -0.4
253,892 - Rv0212c 0.23 +0.1
253,892 - Rv0212c 0.23 -1.0
254,051 - Rv0212c 0.39 -0.4
254,334 - Rv0212c 0.68 -0.1
254,585 + -0.7
254,755 - -0.7
254,854 + Rv0213c 0.17 -0.4
254,854 + Rv0213c 0.17 -1.0
254,854 + Rv0213c 0.17 -0.2
254,854 + Rv0213c 0.17 +1.5
254,910 - Rv0213c 0.21 -0.3
254,910 - Rv0213c 0.21 -0.0
254,911 + Rv0213c 0.21 -1.6
254,978 + Rv0213c 0.26 +1.0
254,978 + Rv0213c 0.26 -0.2
254,979 - Rv0213c 0.26 -0.2
255,089 - Rv0213c 0.34 -0.0
255,272 + Rv0213c 0.48 -2.0
255,273 - Rv0213c 0.48 -0.4
255,295 - Rv0213c 0.50 -0.6
255,311 - Rv0213c 0.51 +0.8
255,381 + Rv0213c 0.57 -0.0
255,381 + Rv0213c 0.57 -2.0
255,429 - Rv0213c 0.60 -1.3
255,573 + Rv0213c 0.71 -0.6
255,573 + Rv0213c 0.71 -0.7
255,697 + Rv0213c 0.81 -0.5
255,697 + Rv0213c 0.81 -0.1
255,697 + Rv0213c 0.81 -0.8
255,831 + -0.6
255,982 + -1.0
255,982 + -0.7
256,018 + -0.5
256,019 - -1.1
256,019 - -0.1
256,082 + +1.5
256,176 - -0.5
256,176 - -0.6
256,209 - +0.2
256,209 - +1.1
256,376 + Rv0214 0.19 -2.5
256,377 - Rv0214 0.19 +0.9
256,380 - Rv0214 0.20 -0.7
256,421 + Rv0214 0.22 -0.4
256,421 + Rv0214 0.22 +1.5
256,422 - Rv0214 0.22 +1.5
256,635 - Rv0214 0.35 -0.7
256,755 + Rv0214 0.43 -0.9
256,756 - Rv0214 0.43 -0.4
256,757 + Rv0214 0.43 +0.0
256,758 - Rv0214 0.43 +0.9
256,779 - Rv0214 0.44 -0.8

Or see this region's nucleotide sequence