Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3144c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3142c and Rv3143 are separated by 107 nucleotidesRv3143 and Rv3144c are separated by 32 nucleotidesRv3144c and Rv3145 are separated by 364 nucleotidesRv3145 and Rv3146 are separated by 8 nucleotides Rv3142c: Rv3142c - Hypothetical protein, at 3,509,118 to 3,509,546 Rv3142c Rv3143: Rv3143 - Probable response regulator, at 3,509,654 to 3,510,055 Rv3143 Rv3144c: Rv3144c - PPE family protein PPE52, at 3,510,088 to 3,511,317 Rv3144c Rv3145: Rv3145 - Probable NADH dehydrogenase I (chain A) NuoA (NADH-ubiquinone oxidoreductase chain A), at 3,511,682 to 3,512,068 Rv3145 Rv3146: Rv3146 - Probable NADH dehydrogenase I (chain B) NuoB (NADH-ubiquinone oxidoreductase chain B), at 3,512,077 to 3,512,631 Rv3146 Position (kb) 3510 3511 3512Strain fitness (log2 ratio) -2 -1 0 1 2at 3509.143 kb on - strandat 3509.210 kb on - strand, within Rv3142cat 3509.210 kb on - strand, within Rv3142cat 3509.296 kb on + strand, within Rv3142cat 3509.296 kb on + strand, within Rv3142cat 3509.425 kb on - strand, within Rv3142cat 3509.430 kb on + strand, within Rv3142cat 3509.452 kb on + strand, within Rv3142cat 3509.453 kb on - strand, within Rv3142cat 3509.453 kb on - strand, within Rv3142cat 3509.489 kb on + strand, within Rv3142cat 3509.489 kb on + strand, within Rv3142cat 3509.546 kb on + strandat 3509.546 kb on + strandat 3509.546 kb on + strandat 3509.547 kb on - strandat 3509.547 kb on - strandat 3509.548 kb on + strandat 3509.548 kb on + strandat 3509.549 kb on - strandat 3509.549 kb on - strandat 3509.574 kb on + strandat 3509.575 kb on - strandat 3509.575 kb on - strandat 3509.583 kb on + strandat 3509.583 kb on + strandat 3509.584 kb on - strandat 3509.641 kb on - strandat 3509.691 kb on - strandat 3509.771 kb on + strand, within Rv3143at 3509.803 kb on - strand, within Rv3143at 3510.136 kb on + strandat 3510.226 kb on + strand, within Rv3144cat 3510.227 kb on - strand, within Rv3144cat 3510.227 kb on - strand, within Rv3144cat 3510.439 kb on - strand, within Rv3144cat 3510.528 kb on + strand, within Rv3144cat 3510.590 kb on - strand, within Rv3144cat 3510.630 kb on + strand, within Rv3144cat 3510.651 kb on - strand, within Rv3144cat 3510.857 kb on + strand, within Rv3144cat 3510.899 kb on + strand, within Rv3144cat 3511.104 kb on - strand, within Rv3144cat 3511.416 kb on + strandat 3511.416 kb on + strandat 3511.427 kb on + strandat 3511.441 kb on + strandat 3511.441 kb on + strandat 3511.441 kb on + strandat 3511.530 kb on + strandat 3511.530 kb on + strandat 3511.530 kb on + strandat 3511.530 kb on + strandat 3511.530 kb on + strandat 3511.530 kb on + strandat 3511.531 kb on - strandat 3511.531 kb on - strandat 3511.531 kb on - strandat 3511.531 kb on - strandat 3511.576 kb on + strandat 3511.691 kb on + strandat 3511.691 kb on + strandat 3511.691 kb on + strandat 3511.692 kb on - strandat 3511.692 kb on - strandat 3511.695 kb on + strandat 3511.707 kb on + strandat 3511.825 kb on + strand, within Rv3145at 3511.889 kb on + strand, within Rv3145at 3511.889 kb on + strand, within Rv3145at 3511.890 kb on - strand, within Rv3145at 3511.890 kb on - strand, within Rv3145at 3511.890 kb on - strand, within Rv3145at 3511.893 kb on - strand, within Rv3145at 3511.893 kb on - strand, within Rv3145at 3511.893 kb on - strand, within Rv3145at 3512.002 kb on - strand, within Rv3145at 3512.033 kb on + strandat 3512.033 kb on + strandat 3512.034 kb on - strandat 3512.034 kb on - strandat 3512.034 kb on - strandat 3512.140 kb on + strand, within Rv3146

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,509,143 - -0.0
3,509,210 - Rv3142c 0.21 -0.4
3,509,210 - Rv3142c 0.21 -0.7
3,509,296 + Rv3142c 0.41 +0.0
3,509,296 + Rv3142c 0.41 -2.0
3,509,425 - Rv3142c 0.72 -0.1
3,509,430 + Rv3142c 0.73 -0.9
3,509,452 + Rv3142c 0.78 -0.2
3,509,453 - Rv3142c 0.78 +0.8
3,509,453 - Rv3142c 0.78 +0.3
3,509,489 + Rv3142c 0.86 -0.2
3,509,489 + Rv3142c 0.86 +0.1
3,509,546 + -0.3
3,509,546 + +0.0
3,509,546 + +0.1
3,509,547 - -1.1
3,509,547 - -1.4
3,509,548 + +1.1
3,509,548 + +0.1
3,509,549 - -1.3
3,509,549 - -0.7
3,509,574 + +1.6
3,509,575 - -0.8
3,509,575 - -0.7
3,509,583 + -1.1
3,509,583 + +0.4
3,509,584 - +0.4
3,509,641 - +1.7
3,509,691 - +0.7
3,509,771 + Rv3143 0.29 -1.6
3,509,803 - Rv3143 0.37 +0.9
3,510,136 + +1.2
3,510,226 + Rv3144c 0.11 -1.1
3,510,227 - Rv3144c 0.11 -0.4
3,510,227 - Rv3144c 0.11 -0.3
3,510,439 - Rv3144c 0.29 -1.0
3,510,528 + Rv3144c 0.36 +0.9
3,510,590 - Rv3144c 0.41 -0.6
3,510,630 + Rv3144c 0.44 -0.1
3,510,651 - Rv3144c 0.46 -0.1
3,510,857 + Rv3144c 0.63 -0.5
3,510,899 + Rv3144c 0.66 -1.3
3,511,104 - Rv3144c 0.83 -0.2
3,511,416 + -0.5
3,511,416 + -1.1
3,511,427 + -0.0
3,511,441 + -1.3
3,511,441 + +2.3
3,511,441 + -0.2
3,511,530 + -1.3
3,511,530 + -0.5
3,511,530 + -0.4
3,511,530 + -1.2
3,511,530 + +1.9
3,511,530 + -0.0
3,511,531 - -0.2
3,511,531 - -0.8
3,511,531 - -0.9
3,511,531 - -0.9
3,511,576 + +0.0
3,511,691 + -0.6
3,511,691 + +1.9
3,511,691 + +0.2
3,511,692 - -0.9
3,511,692 - -0.6
3,511,695 + -0.5
3,511,707 + +1.9
3,511,825 + Rv3145 0.37 +1.9
3,511,889 + Rv3145 0.53 +0.4
3,511,889 + Rv3145 0.53 +0.2
3,511,890 - Rv3145 0.54 -0.3
3,511,890 - Rv3145 0.54 -0.8
3,511,890 - Rv3145 0.54 -0.4
3,511,893 - Rv3145 0.55 -0.2
3,511,893 - Rv3145 0.55 -0.4
3,511,893 - Rv3145 0.55 +1.6
3,512,002 - Rv3145 0.83 -0.2
3,512,033 + -2.1
3,512,033 + +1.1
3,512,034 - +0.8
3,512,034 - -1.4
3,512,034 - -0.5
3,512,140 + Rv3146 0.11 -0.2

Or see this region's nucleotide sequence