Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1586c

Experiment: 7H9 with Zinc Pyrithione 0.00072 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1583c and Rv1584c overlap by 4 nucleotidesRv1584c and Rv1585c are separated by 55 nucleotidesRv1585c and Rv1586c overlap by 4 nucleotidesRv1586c and Rv1587c overlap by 344 nucleotidesRv1587c and Rv1588c are separated by 4 nucleotides Rv1583c: Rv1583c - Probable PhiRv1 phage protein, at 1,785,912 to 1,786,310 Rv1583c Rv1584c: Rv1584c - Possible PhiRv1 phage protein, at 1,786,307 to 1,786,528 Rv1584c Rv1585c: Rv1585c - Possible phage PhiRv1 protein, at 1,786,584 to 1,787,099 Rv1585c Rv1586c: Rv1586c - Probable PhiRv1 integrase, at 1,787,096 to 1,788,505 Rv1586c Rv1587c: Rv1587c - Partial REP13E12 repeat protein, at 1,788,162 to 1,789,163 Rv1587c Rv1588c: Rv1588c - Partial REP13E12 repeat protein, at 1,789,168 to 1,789,836 Rv1588c Position (kb) 1787 1788 1789Strain fitness (log2 ratio) -2 -1 0 1at 1786.410 kb on + strand, within Rv1584cat 1786.410 kb on + strand, within Rv1584cat 1786.411 kb on - strand, within Rv1584cat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.592 kb on + strandat 1786.614 kb on + strandat 1786.706 kb on - strand, within Rv1585cat 1786.974 kb on + strand, within Rv1585cat 1787.598 kb on + strand, within Rv1586cat 1787.599 kb on - strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.803 kb on + strand, within Rv1586cat 1787.804 kb on - strand, within Rv1586cat 1787.804 kb on - strand, within Rv1586cat 1787.804 kb on - strand, within Rv1586cat 1787.804 kb on - strand, within Rv1586cat 1787.805 kb on + strand, within Rv1586cat 1787.805 kb on + strand, within Rv1586cat 1787.805 kb on + strand, within Rv1586cat 1787.806 kb on - strand, within Rv1586cat 1787.806 kb on - strand, within Rv1586cat 1787.952 kb on + strand, within Rv1586cat 1787.953 kb on - strand, within Rv1586cat 1788.015 kb on + strand, within Rv1586cat 1788.015 kb on + strand, within Rv1586cat 1788.404 kb on + strandat 1788.405 kb on - strandat 1788.405 kb on - strandat 1788.471 kb on + strandat 1788.471 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Zinc Pyrithione 0.00072 mM
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1,786,410 + Rv1584c 0.46 -0.0
1,786,410 + Rv1584c 0.46 -0.1
1,786,411 - Rv1584c 0.47 -0.9
1,786,515 + -0.4
1,786,515 + +0.1
1,786,515 + -0.7
1,786,515 + -0.4
1,786,515 + +1.1
1,786,592 + -0.4
1,786,614 + -1.7
1,786,706 - Rv1585c 0.24 -0.8
1,786,974 + Rv1585c 0.76 -0.4
1,787,598 + Rv1586c 0.36 +0.5
1,787,599 - Rv1586c 0.36 +1.5
1,787,803 + Rv1586c 0.50 +0.8
1,787,803 + Rv1586c 0.50 +0.0
1,787,803 + Rv1586c 0.50 +0.2
1,787,803 + Rv1586c 0.50 +0.7
1,787,803 + Rv1586c 0.50 -0.1
1,787,803 + Rv1586c 0.50 -0.2
1,787,803 + Rv1586c 0.50 -1.3
1,787,804 - Rv1586c 0.50 +0.4
1,787,804 - Rv1586c 0.50 -0.2
1,787,804 - Rv1586c 0.50 +0.0
1,787,804 - Rv1586c 0.50 -0.5
1,787,805 + Rv1586c 0.50 -0.3
1,787,805 + Rv1586c 0.50 -2.0
1,787,805 + Rv1586c 0.50 -0.5
1,787,806 - Rv1586c 0.50 +0.7
1,787,806 - Rv1586c 0.50 -0.1
1,787,952 + Rv1586c 0.61 -0.2
1,787,953 - Rv1586c 0.61 +0.1
1,788,015 + Rv1586c 0.65 -1.9
1,788,015 + Rv1586c 0.65 +1.0
1,788,404 + +0.1
1,788,405 - -1.3
1,788,405 - +1.5
1,788,471 + -0.6
1,788,471 + +0.6

Or see this region's nucleotide sequence