Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1582c

Experiment: 7H9 with Irgasan 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1579c and Rv1580c overlap by 4 nucleotidesRv1580c and Rv1581c are separated by 13 nucleotidesRv1581c and Rv1582c are separated by 195 nucleotidesRv1582c and Rv1583c overlap by 1 nucleotidesRv1583c and Rv1584c overlap by 4 nucleotidesRv1584c and Rv1585c are separated by 55 nucleotides Rv1579c: Rv1579c - Probable PhiRv1 phage protein, at 1,783,309 to 1,783,623 Rv1579c Rv1580c: Rv1580c - Probable PhiRv1 phage protein, at 1,783,620 to 1,783,892 Rv1580c Rv1581c: Rv1581c - Probable PhiRv1 phage protein, at 1,783,906 to 1,784,301 Rv1581c Rv1582c: Rv1582c - Probable PhiRv1 phage protein, at 1,784,497 to 1,785,912 Rv1582c Rv1583c: Rv1583c - Probable PhiRv1 phage protein, at 1,785,912 to 1,786,310 Rv1583c Rv1584c: Rv1584c - Possible PhiRv1 phage protein, at 1,786,307 to 1,786,528 Rv1584c Rv1585c: Rv1585c - Possible phage PhiRv1 protein, at 1,786,584 to 1,787,099 Rv1585c Position (kb) 1784 1785 1786Strain fitness (log2 ratio) -2 -1 0 1 2at 1783.783 kb on + strand, within Rv1580cat 1783.783 kb on + strand, within Rv1580cat 1783.783 kb on + strand, within Rv1580cat 1783.783 kb on + strand, within Rv1580cat 1783.784 kb on - strand, within Rv1580cat 1783.920 kb on + strandat 1783.920 kb on + strandat 1784.198 kb on + strand, within Rv1581cat 1784.199 kb on - strand, within Rv1581cat 1784.199 kb on - strand, within Rv1581cat 1784.244 kb on - strand, within Rv1581cat 1784.369 kb on - strandat 1784.369 kb on - strandat 1784.489 kb on + strandat 1784.673 kb on + strand, within Rv1582cat 1784.673 kb on + strand, within Rv1582cat 1784.674 kb on - strand, within Rv1582cat 1784.677 kb on - strand, within Rv1582cat 1784.732 kb on - strand, within Rv1582cat 1784.753 kb on + strand, within Rv1582cat 1785.304 kb on + strand, within Rv1582cat 1785.308 kb on - strand, within Rv1582cat 1785.424 kb on + strand, within Rv1582cat 1785.551 kb on - strand, within Rv1582cat 1786.410 kb on + strand, within Rv1584cat 1786.410 kb on + strand, within Rv1584cat 1786.411 kb on - strand, within Rv1584cat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.515 kb on + strandat 1786.592 kb on + strandat 1786.614 kb on + strandat 1786.706 kb on - strand, within Rv1585c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Irgasan 0.065 mM
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1,783,783 + Rv1580c 0.60 +0.5
1,783,783 + Rv1580c 0.60 -0.7
1,783,783 + Rv1580c 0.60 -0.4
1,783,783 + Rv1580c 0.60 -0.8
1,783,784 - Rv1580c 0.60 -1.6
1,783,920 + +0.0
1,783,920 + -0.1
1,784,198 + Rv1581c 0.74 -2.1
1,784,199 - Rv1581c 0.74 +2.6
1,784,199 - Rv1581c 0.74 -0.8
1,784,244 - Rv1581c 0.85 -0.1
1,784,369 - -1.1
1,784,369 - +0.2
1,784,489 + -0.5
1,784,673 + Rv1582c 0.12 +1.2
1,784,673 + Rv1582c 0.12 -0.2
1,784,674 - Rv1582c 0.12 -0.8
1,784,677 - Rv1582c 0.13 -0.2
1,784,732 - Rv1582c 0.17 -1.5
1,784,753 + Rv1582c 0.18 -0.9
1,785,304 + Rv1582c 0.57 -1.2
1,785,308 - Rv1582c 0.57 -1.5
1,785,424 + Rv1582c 0.65 +0.6
1,785,551 - Rv1582c 0.74 -0.9
1,786,410 + Rv1584c 0.46 -0.0
1,786,410 + Rv1584c 0.46 -0.2
1,786,411 - Rv1584c 0.47 -0.1
1,786,515 + -0.8
1,786,515 + -0.1
1,786,515 + -0.1
1,786,515 + -0.3
1,786,515 + +0.0
1,786,592 + -0.6
1,786,614 + +0.4
1,786,706 - Rv1585c 0.24 -0.3

Or see this region's nucleotide sequence