Experiment: 7H9 with Irgasan 0.065 mM
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0978c and Rv0979c are separated by 313 nucleotides Rv0979c and Rv0979A are separated by 21 nucleotides Rv0979A and Rv0980c are separated by 18 nucleotides Rv0980c and Rv0981 are separated by 370 nucleotides
Rv0978c: Rv0978c - PE-PGRS family protein PE_PGRS17, at 1,093,361 to 1,094,356
Rv0978c
Rv0979c: Rv0979c - Hypothetical protein, at 1,094,670 to 1,094,864
Rv0979c
Rv0979A: Rv0979A - 50S ribosomal protein L32 RpmF, at 1,094,886 to 1,095,059
Rv0979A
Rv0980c: Rv0980c - PE-PGRS family protein PE_PGRS18, at 1,095,078 to 1,096,451
Rv0980c
Rv0981: Rv0981 - Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein), at 1,096,822 to 1,097,508
Rv0981
Position (kb)
1095
1096
1097 Strain fitness (log2 ratio)
-1
0
1
2 at 1094.576 kb on + strand at 1094.576 kb on + strand at 1094.577 kb on - strand at 1095.081 kb on + strand at 1095.082 kb on - strand at 1095.082 kb on - strand at 1095.149 kb on + strand at 1095.149 kb on + strand at 1095.286 kb on + strand, within Rv0980c at 1095.286 kb on + strand, within Rv0980c at 1095.286 kb on + strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.287 kb on - strand, within Rv0980c at 1095.536 kb on - strand, within Rv0980c at 1095.536 kb on - strand, within Rv0980c at 1095.536 kb on - strand, within Rv0980c at 1095.536 kb on - strand, within Rv0980c at 1096.205 kb on + strand, within Rv0980c at 1096.205 kb on + strand, within Rv0980c at 1096.205 kb on + strand, within Rv0980c at 1096.768 kb on + strand at 1096.769 kb on - strand at 1096.769 kb on - strand at 1097.114 kb on - strand, within Rv0981 at 1097.118 kb on - strand, within Rv0981 at 1097.118 kb on - strand, within Rv0981 at 1097.364 kb on - strand, within Rv0981 at 1097.364 kb on - strand, within Rv0981 at 1097.416 kb on + strand, within Rv0981 at 1097.417 kb on - strand, within Rv0981 at 1097.420 kb on + strand, within Rv0981 at 1097.420 kb on + strand, within Rv0981 at 1097.421 kb on - strand, within Rv0981 at 1097.421 kb on - strand, within Rv0981 at 1097.421 kb on - strand, within Rv0981
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Irgasan 0.065 mM remove 1,094,576 + +0.8 1,094,576 + -0.3 1,094,577 - -0.3 1,095,081 + +0.1 1,095,082 - -0.1 1,095,082 - +0.8 1,095,149 + -1.0 1,095,149 + -0.2 1,095,286 + Rv0980c 0.15 -0.3 1,095,286 + Rv0980c 0.15 +1.0 1,095,286 + Rv0980c 0.15 +0.6 1,095,287 - Rv0980c 0.15 -0.5 1,095,287 - Rv0980c 0.15 +0.5 1,095,287 - Rv0980c 0.15 -1.2 1,095,287 - Rv0980c 0.15 +0.5 1,095,287 - Rv0980c 0.15 -0.1 1,095,287 - Rv0980c 0.15 +0.5 1,095,287 - Rv0980c 0.15 +0.8 1,095,536 - Rv0980c 0.33 +1.2 1,095,536 - Rv0980c 0.33 -0.1 1,095,536 - Rv0980c 0.33 +1.0 1,095,536 - Rv0980c 0.33 -0.1 1,096,205 + Rv0980c 0.82 +0.8 1,096,205 + Rv0980c 0.82 +1.4 1,096,205 + Rv0980c 0.82 -0.0 1,096,768 + +0.7 1,096,769 - -0.9 1,096,769 - -1.3 1,097,114 - Rv0981 0.43 +0.5 1,097,118 - Rv0981 0.43 -1.6 1,097,118 - Rv0981 0.43 +1.3 1,097,364 - Rv0981 0.79 -0.5 1,097,364 - Rv0981 0.79 -0.3 1,097,416 + Rv0981 0.86 +0.0 1,097,417 - Rv0981 0.87 -0.2 1,097,420 + Rv0981 0.87 +0.9 1,097,420 + Rv0981 0.87 +0.0 1,097,421 - Rv0981 0.87 -0.2 1,097,421 - Rv0981 0.87 +1.8 1,097,421 - Rv0981 0.87 +0.4
Or see this region's nucleotide sequence