Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0598c

Experiment: 7H9 with Irgasan 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0597c and Rv0598c are separated by 250 nucleotidesRv0598c and Rv0599c overlap by 4 nucleotidesRv0599c and Rv0600c are separated by 103 nucleotidesRv0600c and Rv0601c are separated by 113 nucleotides Rv0597c: Rv0597c - Conserved hypothetical protein, at 695,668 to 696,903 Rv0597c Rv0598c: Rv0598c - Possible toxin VapC27. Contains PIN domain., at 697,154 to 697,567 Rv0598c Rv0599c: Rv0599c - Possible antitoxin VapB27, at 697,564 to 697,800 Rv0599c Rv0600c: Rv0600c - Two component sensor kinase [second part], at 697,904 to 698,410 Rv0600c Rv0601c: Rv0601c - Two component sensor kinase [first part], at 698,524 to 698,994 Rv0601c Position (kb) 697 698Strain fitness (log2 ratio) -2 -1 0 1at 696.326 kb on + strand, within Rv0597cat 696.327 kb on - strand, within Rv0597cat 696.327 kb on - strand, within Rv0597cat 696.327 kb on - strand, within Rv0597cat 696.327 kb on - strand, within Rv0597cat 696.703 kb on + strand, within Rv0597cat 696.914 kb on + strandat 697.270 kb on - strand, within Rv0598cat 697.366 kb on + strand, within Rv0598cat 697.432 kb on - strand, within Rv0598cat 697.708 kb on + strand, within Rv0599cat 697.806 kb on + strandat 697.905 kb on + strandat 697.916 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Irgasan 0.065 mM
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696,326 + Rv0597c 0.53 -1.2
696,327 - Rv0597c 0.53 -0.3
696,327 - Rv0597c 0.53 -0.3
696,327 - Rv0597c 0.53 +0.0
696,327 - Rv0597c 0.53 -0.3
696,703 + Rv0597c 0.84 -0.3
696,914 + -2.7
697,270 - Rv0598c 0.28 +0.1
697,366 + Rv0598c 0.51 -0.9
697,432 - Rv0598c 0.67 -2.0
697,708 + Rv0599c 0.61 -1.5
697,806 + -0.8
697,905 + -0.4
697,916 - -0.2

Or see this region's nucleotide sequence