Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1920

Experiment: 7H9 with Irgasan 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1919c and Rv1920 are separated by 97 nucleotidesRv1920 and Rv1921c are separated by 37 nucleotides Rv1919c: Rv1919c - Conserved protein, at 2,171,061 to 2,171,525 Rv1919c Rv1920: Rv1920 - Probable membrane protein, at 2,171,623 to 2,172,486 Rv1920 Rv1921c: Rv1921c - Probable conserved lipoprotein LppF, at 2,172,524 to 2,173,795 Rv1921c Position (kb) 2171 2172 2173Strain fitness (log2 ratio) -2 -1 0 1 2at 2171.051 kb on + strandat 2171.222 kb on + strand, within Rv1919cat 2171.222 kb on + strand, within Rv1919cat 2171.222 kb on + strand, within Rv1919cat 2171.222 kb on + strand, within Rv1919cat 2171.278 kb on + strand, within Rv1919cat 2171.279 kb on - strand, within Rv1919cat 2171.344 kb on - strand, within Rv1919cat 2171.344 kb on - strand, within Rv1919cat 2171.561 kb on + strandat 2171.576 kb on + strandat 2171.581 kb on + strandat 2171.607 kb on + strandat 2171.607 kb on + strandat 2171.652 kb on + strandat 2171.676 kb on + strandat 2171.677 kb on - strandat 2171.677 kb on - strandat 2171.677 kb on - strandat 2171.758 kb on - strand, within Rv1920at 2171.771 kb on - strand, within Rv1920at 2172.061 kb on + strand, within Rv1920at 2172.298 kb on + strand, within Rv1920at 2172.298 kb on + strand, within Rv1920at 2172.301 kb on + strand, within Rv1920at 2172.621 kb on - strandat 2172.621 kb on - strandat 2172.624 kb on + strandat 2172.624 kb on + strandat 2172.625 kb on - strandat 2172.625 kb on - strandat 2172.653 kb on - strand, within Rv1921cat 2172.703 kb on - strand, within Rv1921cat 2172.900 kb on + strand, within Rv1921cat 2173.019 kb on + strand, within Rv1921cat 2173.019 kb on + strand, within Rv1921cat 2173.020 kb on - strand, within Rv1921cat 2173.020 kb on - strand, within Rv1921cat 2173.020 kb on - strand, within Rv1921cat 2173.099 kb on + strand, within Rv1921cat 2173.100 kb on - strand, within Rv1921cat 2173.125 kb on + strand, within Rv1921cat 2173.126 kb on - strand, within Rv1921cat 2173.126 kb on - strand, within Rv1921cat 2173.137 kb on + strand, within Rv1921cat 2173.273 kb on - strand, within Rv1921cat 2173.459 kb on - strand, within Rv1921c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Irgasan 0.065 mM
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2,171,051 + -0.8
2,171,222 + Rv1919c 0.35 -1.2
2,171,222 + Rv1919c 0.35 -0.1
2,171,222 + Rv1919c 0.35 -1.2
2,171,222 + Rv1919c 0.35 -0.8
2,171,278 + Rv1919c 0.47 +0.0
2,171,279 - Rv1919c 0.47 +0.5
2,171,344 - Rv1919c 0.61 +0.2
2,171,344 - Rv1919c 0.61 -1.6
2,171,561 + -0.6
2,171,576 + +0.5
2,171,581 + -2.4
2,171,607 + -0.2
2,171,607 + -0.7
2,171,652 + -1.7
2,171,676 + +1.8
2,171,677 - +0.4
2,171,677 - -1.0
2,171,677 - -0.2
2,171,758 - Rv1920 0.16 -0.5
2,171,771 - Rv1920 0.17 -0.9
2,172,061 + Rv1920 0.51 -0.4
2,172,298 + Rv1920 0.78 -0.7
2,172,298 + Rv1920 0.78 -0.3
2,172,301 + Rv1920 0.78 -0.4
2,172,621 - +0.3
2,172,621 - +0.8
2,172,624 + -0.4
2,172,624 + -2.2
2,172,625 - -0.4
2,172,625 - -0.2
2,172,653 - Rv1921c 0.10 +0.7
2,172,703 - Rv1921c 0.14 -0.1
2,172,900 + Rv1921c 0.30 -0.1
2,173,019 + Rv1921c 0.39 -1.0
2,173,019 + Rv1921c 0.39 -0.2
2,173,020 - Rv1921c 0.39 +0.2
2,173,020 - Rv1921c 0.39 -0.2
2,173,020 - Rv1921c 0.39 -0.7
2,173,099 + Rv1921c 0.45 +0.7
2,173,100 - Rv1921c 0.45 -0.6
2,173,125 + Rv1921c 0.47 -0.1
2,173,126 - Rv1921c 0.47 -0.3
2,173,126 - Rv1921c 0.47 +0.5
2,173,137 + Rv1921c 0.48 -0.0
2,173,273 - Rv1921c 0.59 +0.2
2,173,459 - Rv1921c 0.74 +0.3

Or see this region's nucleotide sequence