Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1003

Experiment: 7H9 with Irgasan 0.065 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1002c and Rv1003 are separated by 82 nucleotidesRv1003 and Rv1004c are separated by 9 nucleotides Rv1002c: Rv1002c - Conserved membrane protein, at 1,118,428 to 1,119,939 Rv1002c Rv1003: Rv1003 - Conserved protein, at 1,120,022 to 1,120,879 Rv1003 Rv1004c: Rv1004c - Probable membrane protein, at 1,120,889 to 1,122,148 Rv1004c Position (kb) 1120 1121Strain fitness (log2 ratio) -2 -1 0 1 2at 1120.009 kb on + strandat 1120.010 kb on - strandat 1120.360 kb on - strand, within Rv1003at 1120.878 kb on - strandat 1120.878 kb on - strandat 1120.890 kb on + strandat 1120.897 kb on + strandat 1120.897 kb on + strandat 1120.897 kb on + strandat 1120.898 kb on - strandat 1121.547 kb on + strand, within Rv1004cat 1121.547 kb on + strand, within Rv1004cat 1121.726 kb on + strand, within Rv1004cat 1121.726 kb on + strand, within Rv1004c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Irgasan 0.065 mM
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1,120,009 + -0.1
1,120,010 - -0.5
1,120,360 - Rv1003 0.39 -1.9
1,120,878 - +0.2
1,120,878 - +0.6
1,120,890 + +1.0
1,120,897 + -0.1
1,120,897 + +1.8
1,120,897 + +0.4
1,120,898 - -0.3
1,121,547 + Rv1004c 0.52 +0.8
1,121,547 + Rv1004c 0.52 -1.2
1,121,726 + Rv1004c 0.66 +0.1
1,121,726 + Rv1004c 0.66 +0.5

Or see this region's nucleotide sequence