Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0535

Experiment: 7H9 with Irgasan 0.065 mM

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0533c and Rv0534c are separated by 81 nucleotidesRv0534c and Rv0535 are separated by 16 nucleotidesRv0535 and Rv0536 overlap by 4 nucleotides Rv0533c: Rv0533c - 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III), at 624,473 to 625,480 Rv0533c Rv0534c: Rv0534c - 1,4-dihydroxy-2-naphthoate octaprenyltransferase MenA (DHNA-octaprenyltransferase), at 625,562 to 626,440 Rv0534c Rv0535: Rv0535 - Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase), at 626,457 to 627,251 Rv0535 Rv0536: Rv0536 - Probable UDP-glucose 4-epimerase GalE3 (galactowaldenase) (UDP-galactose 4-epimerase) (uridine diphosphate galactose 4-epimerase) (uridine diphospho-galactose 4-epimerase), at 627,248 to 628,288 Rv0536 Position (kb) 626 627 628Strain fitness (log2 ratio) -1 0 1at 625.481 kb on - strandat 625.489 kb on + strandat 625.489 kb on + strandat 625.490 kb on - strandat 625.490 kb on - strandat 625.490 kb on - strandat 625.563 kb on + strandat 625.564 kb on - strandat 626.456 kb on + strandat 626.457 kb on - strandat 626.505 kb on + strandat 626.506 kb on - strandat 626.506 kb on - strandat 626.811 kb on + strand, within Rv0535at 626.812 kb on - strand, within Rv0535at 626.812 kb on - strand, within Rv0535at 626.812 kb on - strand, within Rv0535at 627.620 kb on + strand, within Rv0536at 627.620 kb on + strand, within Rv0536at 627.621 kb on - strand, within Rv0536at 627.621 kb on - strand, within Rv0536at 627.774 kb on - strand, within Rv0536at 627.866 kb on + strand, within Rv0536at 627.867 kb on - strand, within Rv0536at 628.163 kb on + strand, within Rv0536

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Irgasan 0.065 mM
remove
625,481 - -0.7
625,489 + -0.5
625,489 + -0.2
625,490 - -0.5
625,490 - -0.2
625,490 - -0.2
625,563 + -0.9
625,564 - +0.3
626,456 + +0.1
626,457 - +0.1
626,505 + -0.1
626,506 - -0.3
626,506 - -0.1
626,811 + Rv0535 0.45 -1.5
626,812 - Rv0535 0.45 -0.6
626,812 - Rv0535 0.45 -0.8
626,812 - Rv0535 0.45 -0.4
627,620 + Rv0536 0.36 -1.2
627,620 + Rv0536 0.36 -0.2
627,621 - Rv0536 0.36 -0.2
627,621 - Rv0536 0.36 -1.0
627,774 - Rv0536 0.51 -0.1
627,866 + Rv0536 0.59 +0.2
627,867 - Rv0536 0.59 -0.1
628,163 + Rv0536 0.88 +0.5

Or see this region's nucleotide sequence