Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3877

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
4,354,059	-		Rv3876	0.52	-0.3
4,354,210	+		Rv3876	0.60	+1.2
4,354,211	-		Rv3876	0.60	-0.7
4,354,258	+		Rv3876	0.62	+0.4
4,354,462	+		Rv3876	0.73	-0.6
4,354,463	-		Rv3876	0.73	-0.5
4,354,463	-		Rv3876	0.73	-0.1
4,354,486	-		Rv3876	0.74	-1.0
4,354,486	-		Rv3876	0.74	-0.1
4,354,528	+		Rv3876	0.76	-0.5
4,354,528	+		Rv3876	0.76	-0.6
4,354,528	+		Rv3876	0.76	+0.2
4,354,529	-		Rv3876	0.76	+1.4
4,354,529	-		Rv3876	0.76	-0.6
4,354,597	+		Rv3876	0.79	+0.1
4,354,598	-		Rv3876	0.79	-0.2
4,354,824	+				+2.7
4,354,824	+				-0.9
4,354,824	+				-0.3
4,354,938	+				-0.2
4,354,942	+				-0.2
4,354,943	-				-0.0
4,355,145	+				+0.6
4,355,145	+				-0.1
4,355,145	+				+0.8
4,355,148	-				-0.3
4,355,148	-				-0.3
4,355,353	-		Rv3877	0.23	-0.2
4,355,513	+		Rv3877	0.33	-1.4
4,355,564	-		Rv3877	0.36	-0.3
4,355,589	+		Rv3877	0.38	-1.4
4,355,589	+		Rv3877	0.38	+0.0
4,355,617	+		Rv3877	0.40	+0.4
4,355,632	-		Rv3877	0.41	+0.3
4,356,118	-		Rv3877	0.72	+0.1
4,356,187	+		Rv3877	0.77	-0.4
4,356,187	+		Rv3877	0.77	+0.3
4,356,188	-		Rv3877	0.77	-2.9
4,356,339	+		Rv3877	0.87	-0.5
4,356,340	-		Rv3877	0.87	-0.6
4,356,340	-		Rv3877	0.87	+0.1
4,356,340	-		Rv3877	0.87	-0.4
4,356,340	-		Rv3877	0.87	+0.9
4,356,340	-		Rv3877	0.87	+0.4
4,356,374	-		Rv3877	0.89	-0.1
4,356,513	+				-1.4
4,356,514	-				-0.4
4,356,514	-				-1.4
4,356,514	-				-0.5
4,356,603	-				-0.3
4,356,677	+				+0.2
4,356,677	+				-0.2
4,356,677	+				+0.4
4,356,677	+				+0.2
4,356,677	+				-0.7
4,356,678	-				-0.2
4,356,678	-				-1.2
4,356,678	-				-0.1
4,356,678	-				-0.6
4,356,678	-				+0.9
4,356,678	-				-0.3
4,356,679	+				+0.7
4,356,680	-				-0.2
4,356,680	-				-0.2
4,356,680	-				-0.0
4,356,812	-		Rv3878	0.14	-0.3
4,356,812	-		Rv3878	0.14	-0.2
4,356,927	+		Rv3878	0.28	+1.4
4,356,970	-		Rv3878	0.33	-1.8
4,356,970	-		Rv3878	0.33	-0.8
4,356,970	-		Rv3878	0.33	+0.1
4,357,533	+				-0.7
4,357,534	-				+1.2
4,357,534	-				-1.2
4,357,534	-				+0.4
4,357,534	-				+0.0