Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3127

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
3,491,186	-		Rv3125c	0.60	-0.6
3,491,431	+		Rv3125c	0.81	+0.6
3,491,432	-		Rv3125c	0.81	+1.2
3,491,545	-				-1.4
3,491,691	-				-1.0
3,491,691	-				-0.4
3,492,142	+				-1.0
3,492,142	+				+0.0
3,492,142	+				+2.6
3,492,525	+		Rv3127	0.37	-0.3
3,492,793	-		Rv3127	0.62	-0.4
3,492,815	-		Rv3127	0.65	-1.7
3,492,907	+		Rv3127	0.73	-0.9
3,493,130	+				+1.0
3,493,143	-				-0.6
3,493,232	+				+0.0
3,493,233	-				+0.6
3,493,328	+		Rv3128c	0.16	-0.4
3,493,559	+		Rv3128c	0.39	-0.3
3,493,637	+		Rv3128c	0.46	-1.1
3,493,638	-		Rv3128c	0.46	-0.8
3,493,642	-		Rv3128c	0.47	-0.4