Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3077

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
3,438,592	+		Rv3075c	0.59	+0.7
3,438,592	+		Rv3075c	0.59	+0.0
3,438,592	+		Rv3075c	0.59	-0.3
3,438,592	+		Rv3075c	0.59	-0.0
3,438,592	+		Rv3075c	0.59	+0.6
3,438,593	-		Rv3075c	0.59	-2.4
3,438,683	+		Rv3075c	0.69	+0.9
3,438,960	+				+0.2
3,438,960	+				-0.7
3,438,960	+				-0.2
3,438,960	+				+1.6
3,438,976	-				+0.6
3,439,015	+				-1.1
3,439,016	-				-2.8
3,439,016	-				+0.1
3,439,235	+		Rv3076	0.34	-0.3
3,439,692	-				-0.2
3,439,692	-				-0.8
3,439,847	-		Rv3077	0.17	+0.7
3,439,880	+		Rv3077	0.19	-0.1
3,440,018	+		Rv3077	0.26	-0.5
3,440,348	+		Rv3077	0.45	-0.9
3,440,348	+		Rv3077	0.45	+2.6
3,440,348	+		Rv3077	0.45	+0.9
3,440,348	+		Rv3077	0.45	-0.0
3,440,348	+		Rv3077	0.45	-0.4
3,440,367	+		Rv3077	0.46	-0.4
3,440,374	+		Rv3077	0.46	+0.5
3,440,390	+		Rv3077	0.47	-1.6
3,440,391	-		Rv3077	0.47	-0.2
3,440,391	-		Rv3077	0.47	-0.3
3,440,391	-		Rv3077	0.47	-0.2
3,440,424	-		Rv3077	0.49	-1.0
3,440,712	+		Rv3077	0.65	+1.8
3,441,028	+		Rv3077	0.82	-0.5
3,441,140	+		Rv3077	0.88	+0.1
3,441,171	-				-1.2
3,441,278	+				-0.5
3,441,279	-				-1.3
3,441,351	-				-0.1
3,441,366	+				+1.6
3,441,367	-				-1.1
3,441,367	-				+0.2
3,441,367	-				+0.9
3,441,367	-				-0.6
3,441,626	-		Rv3078	0.68	-0.3
3,441,771	+				-0.4
3,441,772	-				-1.8
3,441,772	-				+0.2
3,441,811	-				+1.6
3,442,062	+		Rv3079c	0.35	-0.4
3,442,062	+		Rv3079c	0.35	+0.8
3,442,063	-		Rv3079c	0.35	-0.5
3,442,104	+		Rv3079c	0.40	+0.1
3,442,105	-		Rv3079c	0.40	+0.4
3,442,125	+		Rv3079c	0.43	-0.9
3,442,125	+		Rv3079c	0.43	+0.5
3,442,125	+		Rv3079c	0.43	-0.5
3,442,125	+		Rv3079c	0.43	+1.3
3,442,125	+		Rv3079c	0.43	-0.8
3,442,126	-		Rv3079c	0.43	+0.6