Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2973c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Levofloxacin 0.3 ug/mL
3,326,950	+				+0.3
3,327,025	-				-0.3
3,327,126	+		Rv2972c	0.14	-0.7
3,327,127	-		Rv2972c	0.15	-0.4
3,327,288	+		Rv2972c	0.37	-0.6
3,327,288	+		Rv2972c	0.37	-0.1
3,327,369	+		Rv2972c	0.48	+0.4
3,327,369	+		Rv2972c	0.48	-2.4
3,327,370	-		Rv2972c	0.49	-0.3
3,327,426	+		Rv2972c	0.56	+0.3
3,327,426	+		Rv2972c	0.56	+0.5
3,327,426	+		Rv2972c	0.56	-0.8
3,327,426	+		Rv2972c	0.56	-0.5
3,327,426	+		Rv2972c	0.56	+0.1
3,327,427	-		Rv2972c	0.57	-0.1
3,327,427	-		Rv2972c	0.57	-0.4
3,327,720	-				-0.2
3,327,720	-				-0.0
3,327,720	-				-0.4
3,327,741	+				+1.6
3,327,741	+				-1.5
3,327,742	-				-0.8
3,327,742	-				+0.8
3,327,742	-				+0.1
3,327,851	-				-0.9
3,327,854	+				+1.6
3,327,855	-				-0.7
3,328,141	-		Rv2973c	0.18	-2.2
3,328,391	+		Rv2973c	0.30	-0.4
3,329,246	-		Rv2973c	0.68	-1.2
3,329,417	+		Rv2973c	0.76	+0.6
3,329,491	-		Rv2973c	0.79	-0.7
3,329,579	+		Rv2973c	0.83	-0.3
3,329,580	-		Rv2973c	0.83	-0.6
3,329,738	+				+0.4
3,329,739	-				-1.2
3,329,829	-				-0.4
3,329,841	-				-4.0
3,329,935	+				-0.6
3,329,936	-				-1.4
3,330,082	-				-1.5
3,330,375	+		Rv2974c	0.30	+1.3
3,330,408	-		Rv2974c	0.32	+0.2
3,330,408	-		Rv2974c	0.32	+0.9
3,330,440	-		Rv2974c	0.35	-0.7
3,330,440	-		Rv2974c	0.35	-0.0
3,330,440	-		Rv2974c	0.35	+0.8
3,330,480	+		Rv2974c	0.38	+0.6
3,330,481	-		Rv2974c	0.38	+0.1
3,330,751	-		Rv2974c	0.57	-0.4
3,330,751	-		Rv2974c	0.57	+0.0
3,330,751	-		Rv2974c	0.57	+0.2
3,330,757	+		Rv2974c	0.57	+0.8
3,330,758	-		Rv2974c	0.57	+0.1
3,330,758	-		Rv2974c	0.57	-0.3
3,330,859	+		Rv2974c	0.64	+3.2
3,330,860	-		Rv2974c	0.64	-0.9
3,330,860	-		Rv2974c	0.64	-0.3
3,330,860	-		Rv2974c	0.64	-0.7
3,330,860	-		Rv2974c	0.64	+0.2