Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1532c

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1530 and Rv1531 overlap by 4 nucleotidesRv1531 and Rv1532c are separated by 76 nucleotidesRv1532c and Rv1533 are separated by 59 nucleotides Rv1530: Rv1530 - Probable alcohol dehydrogenase Adh, at 1,731,373 to 1,732,476 Rv1530 Rv1531: Rv1531 - Conserved protein, at 1,732,473 to 1,733,039 Rv1531 Rv1532c: Rv1532c - Conserved hypothetical protein, at 1,733,116 to 1,733,550 Rv1532c Rv1533: Rv1533 - Conserved protein, at 1,733,610 to 1,734,737 Rv1533 Position (kb) 1733 1734Strain fitness (log2 ratio) -1 0 1 2at 1732.420 kb on - strandat 1732.707 kb on + strand, within Rv1531at 1732.791 kb on + strand, within Rv1531at 1732.939 kb on + strand, within Rv1531at 1733.118 kb on - strandat 1733.557 kb on + strandat 1733.557 kb on + strandat 1733.557 kb on + strandat 1733.558 kb on - strandat 1733.653 kb on + strandat 1733.736 kb on - strand, within Rv1533at 1733.826 kb on + strand, within Rv1533at 1733.826 kb on + strand, within Rv1533at 1733.826 kb on + strand, within Rv1533at 1733.995 kb on - strand, within Rv1533

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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1,732,420 - +0.4
1,732,707 + Rv1531 0.41 -1.1
1,732,791 + Rv1531 0.56 +1.8
1,732,939 + Rv1531 0.82 -0.8
1,733,118 - +0.2
1,733,557 + -0.8
1,733,557 + +0.6
1,733,557 + +0.4
1,733,558 - +0.0
1,733,653 + -0.8
1,733,736 - Rv1533 0.11 -0.4
1,733,826 + Rv1533 0.19 -0.1
1,733,826 + Rv1533 0.19 -1.3
1,733,826 + Rv1533 0.19 +0.0
1,733,995 - Rv1533 0.34 +0.0

Or see this region's nucleotide sequence