Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2809

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2807 and Rv2808 are separated by 233 nucleotidesRv2808 and Rv2809 are separated by 104 nucleotidesRv2809 and Rv2810c are separated by 21 nucleotidesRv2810c and Rv2811 overlap by 4 nucleotides Rv2807: Rv2807 - Conserved hypothetical protein, at 3,113,658 to 3,114,812 Rv2807 Rv2808: Rv2808 - Hypothetical protein, at 3,115,046 to 3,115,303 Rv2808 Rv2809: Rv2809 - Hypothetical protein, at 3,115,408 to 3,115,719 Rv2809 Rv2810c: Rv2810c - Probable transposase, at 3,115,741 to 3,116,142 Rv2810c Rv2811: Rv2811 - Conserved hypothetical protein, at 3,116,139 to 3,116,747 Rv2811 Position (kb) 3115 3116Strain fitness (log2 ratio) -1 0 1 2at 3114.531 kb on + strand, within Rv2807at 3114.531 kb on + strand, within Rv2807at 3114.567 kb on + strand, within Rv2807at 3114.568 kb on - strand, within Rv2807at 3114.810 kb on + strandat 3114.835 kb on + strandat 3114.835 kb on + strandat 3114.835 kb on + strandat 3115.319 kb on + strandat 3115.340 kb on - strandat 3115.394 kb on - strandat 3115.431 kb on + strandat 3115.604 kb on + strand, within Rv2809at 3115.605 kb on - strand, within Rv2809at 3115.647 kb on + strand, within Rv2809at 3115.648 kb on - strand, within Rv2809at 3115.837 kb on + strand, within Rv2810cat 3115.957 kb on + strand, within Rv2810cat 3115.958 kb on - strand, within Rv2810cat 3115.958 kb on - strand, within Rv2810cat 3115.960 kb on + strand, within Rv2810c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
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3,114,531 + Rv2807 0.76 +0.2
3,114,531 + Rv2807 0.76 -0.5
3,114,567 + Rv2807 0.79 -1.6
3,114,568 - Rv2807 0.79 +0.6
3,114,810 + +0.7
3,114,835 + +0.2
3,114,835 + -0.1
3,114,835 + -1.2
3,115,319 + +0.1
3,115,340 - +0.9
3,115,394 - +2.0
3,115,431 + +0.9
3,115,604 + Rv2809 0.63 -1.1
3,115,605 - Rv2809 0.63 -0.3
3,115,647 + Rv2809 0.77 -1.0
3,115,648 - Rv2809 0.77 -0.5
3,115,837 + Rv2810c 0.24 +0.3
3,115,957 + Rv2810c 0.54 -0.2
3,115,958 - Rv2810c 0.54 -0.4
3,115,958 - Rv2810c 0.54 -1.1
3,115,960 + Rv2810c 0.54 +0.7

Or see this region's nucleotide sequence