Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1279

Experiment: 7H9 with Levofloxacin 0.3 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1278 and Rv1279 are separated by 20 nucleotidesRv1279 and Rv1280c are separated by 16 nucleotides Rv1278: Rv1278 - Hypothetical protein, at 1,427,414 to 1,430,041 Rv1278 Rv1279: Rv1279 - Probable dehydrogenase FAD flavoprotein GMC oxidoreductase, at 1,430,062 to 1,431,648 Rv1279 Rv1280c: Rv1280c - Probable periplasmic oligopeptide-binding lipoprotein OppA, at 1,431,665 to 1,433,440 Rv1280c Position (kb) 1430 1431 1432Strain fitness (log2 ratio) -2 -1 0 1 2at 1429.206 kb on + strand, within Rv1278at 1429.778 kb on + strand, within Rv1278at 1430.034 kb on + strandat 1430.034 kb on + strandat 1430.035 kb on - strandat 1430.081 kb on - strandat 1430.081 kb on - strandat 1430.081 kb on - strandat 1430.081 kb on - strandat 1430.248 kb on + strand, within Rv1279at 1430.407 kb on + strand, within Rv1279at 1431.026 kb on - strand, within Rv1279at 1431.029 kb on + strand, within Rv1279at 1431.030 kb on - strand, within Rv1279at 1431.030 kb on - strand, within Rv1279at 1431.030 kb on - strand, within Rv1279at 1431.277 kb on + strand, within Rv1279at 1431.277 kb on + strand, within Rv1279at 1431.299 kb on + strand, within Rv1279at 1431.460 kb on + strand, within Rv1279at 1431.591 kb on + strandat 1431.591 kb on + strandat 1431.592 kb on - strandat 1431.694 kb on - strandat 1431.694 kb on - strandat 1431.928 kb on - strand, within Rv1280cat 1432.120 kb on - strand, within Rv1280cat 1432.120 kb on - strand, within Rv1280cat 1432.224 kb on + strand, within Rv1280cat 1432.224 kb on + strand, within Rv1280cat 1432.338 kb on + strand, within Rv1280cat 1432.423 kb on - strand, within Rv1280cat 1432.566 kb on + strand, within Rv1280cat 1432.567 kb on - strand, within Rv1280cat 1432.567 kb on - strand, within Rv1280c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Levofloxacin 0.3 ug/mL
remove
1,429,206 + Rv1278 0.68 -1.7
1,429,778 + Rv1278 0.90 -1.0
1,430,034 + -0.1
1,430,034 + -1.2
1,430,035 - -2.1
1,430,081 - -1.0
1,430,081 - -1.8
1,430,081 - +0.4
1,430,081 - +0.5
1,430,248 + Rv1279 0.12 -0.1
1,430,407 + Rv1279 0.22 -0.6
1,431,026 - Rv1279 0.61 -0.4
1,431,029 + Rv1279 0.61 -0.5
1,431,030 - Rv1279 0.61 -0.3
1,431,030 - Rv1279 0.61 -0.7
1,431,030 - Rv1279 0.61 -0.5
1,431,277 + Rv1279 0.77 +1.8
1,431,277 + Rv1279 0.77 -0.9
1,431,299 + Rv1279 0.78 +0.1
1,431,460 + Rv1279 0.88 -1.1
1,431,591 + -0.3
1,431,591 + -0.2
1,431,592 - -0.7
1,431,694 - -0.4
1,431,694 - +1.8
1,431,928 - Rv1280c 0.15 -2.6
1,432,120 - Rv1280c 0.26 +0.1
1,432,120 - Rv1280c 0.26 +0.3
1,432,224 + Rv1280c 0.31 -1.9
1,432,224 + Rv1280c 0.31 -0.4
1,432,338 + Rv1280c 0.38 -0.1
1,432,423 - Rv1280c 0.43 -0.8
1,432,566 + Rv1280c 0.51 -2.7
1,432,567 - Rv1280c 0.51 -0.1
1,432,567 - Rv1280c 0.51 -0.3

Or see this region's nucleotide sequence