Experiment: 7H9 with Linezolid 0.44 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3672c and Rv3673c are separated by 131 nucleotides Rv3673c and Rv3674c overlap by 1 nucleotides Rv3674c and Rv3675 are separated by 107 nucleotides Rv3675 and Rv3676 are separated by 98 nucleotides
Rv3672c: Rv3672c - Conserved hypothetical protein, at 4,113,521 to 4,114,342
Rv3672c
Rv3673c: Rv3673c - Possible membrane-anchored thioredoxin-like protein (thiol-disulfide interchange related protein), at 4,114,474 to 4,115,157
Rv3673c
Rv3674c: Rv3674c - Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)), at 4,115,157 to 4,115,894
Rv3674c
Rv3675: Rv3675 - Possible membrane protein, at 4,116,002 to 4,116,379
Rv3675
Rv3676: Rv3676 - Transcriptional regulatory protein Crp (Crp/Fnr-family), at 4,116,478 to 4,117,152
Rv3676
Position (kb)
4115
4116 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 4114.218 kb on - strand, within Rv3672c at 4114.471 kb on + strand at 4115.158 kb on + strand at 4115.159 kb on - strand at 4115.575 kb on - strand, within Rv3674c at 4115.575 kb on - strand, within Rv3674c at 4115.575 kb on - strand, within Rv3674c at 4115.671 kb on + strand, within Rv3674c at 4115.672 kb on - strand, within Rv3674c at 4115.751 kb on + strand, within Rv3674c at 4115.802 kb on + strand, within Rv3674c at 4115.803 kb on - strand, within Rv3674c at 4115.957 kb on + strand at 4115.958 kb on - strand at 4116.007 kb on + strand at 4116.008 kb on - strand at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.304 kb on + strand, within Rv3675 at 4116.405 kb on + strand at 4116.447 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.44 ug/mL remove 4,114,218 - Rv3672c 0.85 +0.8 4,114,471 + -0.9 4,115,158 + +0.0 4,115,159 - -0.6 4,115,575 - Rv3674c 0.57 -1.0 4,115,575 - Rv3674c 0.57 -0.5 4,115,575 - Rv3674c 0.57 -0.7 4,115,671 + Rv3674c 0.70 -0.4 4,115,672 - Rv3674c 0.70 +0.0 4,115,751 + Rv3674c 0.80 -0.2 4,115,802 + Rv3674c 0.87 -1.2 4,115,803 - Rv3674c 0.88 +0.1 4,115,957 + +1.8 4,115,958 - -1.8 4,116,007 + -1.0 4,116,008 - -0.8 4,116,167 - Rv3675 0.44 -1.2 4,116,167 - Rv3675 0.44 -1.1 4,116,167 - Rv3675 0.44 -1.0 4,116,167 - Rv3675 0.44 -0.7 4,116,304 + Rv3675 0.80 -0.3 4,116,405 + -0.3 4,116,447 + +0.4
Or see this region's nucleotide sequence