Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3192

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
3,558,693	+				-0.7
3,558,729	+				-0.6
3,558,744	-				+0.2
3,558,864	-				-0.4
3,558,864	-				-0.1
3,558,918	-				-0.2
3,558,936	-				+0.0
3,559,049	-				-0.1
3,559,162	+				+0.7
3,559,195	-				+1.7
3,559,296	-				-0.7
3,559,533	+				+1.7
3,559,534	-				+0.4
3,559,775	+		Rv3192	0.46	+0.0
3,559,776	-		Rv3192	0.46	+0.2
3,559,837	-		Rv3192	0.59	-0.4
3,559,841	+		Rv3192	0.60	+1.8
3,559,875	+		Rv3192	0.68	+0.2
3,559,876	-		Rv3192	0.68	+0.3
3,560,341	+				-1.3
3,560,615	+		Rv3193c	0.14	-0.1
3,560,940	-		Rv3193c	0.25	-1.1