Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3190c

Experiment: 7H9 with Linezolid 0.3 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.3 ug/mL
3,554,505	-		Rv3188	0.59	+0.9
3,554,638	-				-0.5
3,554,638	-				-0.2
3,554,696	+				-2.0
3,554,696	+				-0.8
3,554,696	+				-0.7
3,554,696	+				-0.3
3,554,696	+				-1.6
3,554,697	-				+0.3
3,554,950	-		Rv3189	0.50	-0.6
3,554,950	-		Rv3189	0.50	-0.6
3,554,950	-		Rv3189	0.50	-0.6
3,554,984	+		Rv3189	0.55	+0.0
3,554,985	-		Rv3189	0.55	-1.1
3,555,156	+		Rv3189	0.83	+0.5
3,555,261	-				+0.1
3,555,287	-				-0.1
3,555,323	+				+0.3
3,555,324	-				-0.9
3,555,324	-				+1.3
3,555,324	-				+0.0
3,555,461	+				-0.0
3,555,532	-				+0.4
3,555,568	+		Rv3190c	0.12	+0.4
3,555,638	-		Rv3190c	0.17	-0.1
3,555,686	+		Rv3190c	0.21	-1.0
3,556,054	-		Rv3190c	0.50	+2.8
3,556,054	-		Rv3190c	0.50	+0.2
3,556,054	-		Rv3190c	0.50	+0.2
3,556,054	-		Rv3190c	0.50	-0.0
3,556,054	-		Rv3190c	0.50	-0.1
3,556,054	-		Rv3190c	0.50	+0.8
3,556,079	+		Rv3190c	0.52	+0.2
3,556,080	-		Rv3190c	0.52	-0.0
3,556,213	-		Rv3190c	0.62	-0.5
3,556,222	+		Rv3190c	0.63	-0.8
3,556,223	-		Rv3190c	0.63	+0.5
3,556,238	-		Rv3190c	0.64	-0.3
3,556,311	-		Rv3190c	0.70	+0.1
3,556,319	+		Rv3190c	0.71	-0.1
3,556,319	+		Rv3190c	0.71	-0.3
3,556,372	+		Rv3190c	0.75	+0.2
3,556,372	+		Rv3190c	0.75	+1.2
3,556,373	-		Rv3190c	0.75	-0.7
3,556,373	-		Rv3190c	0.75	+0.8
3,556,680	+				+0.8
3,556,690	-				-0.0
3,556,699	+				+0.2
3,556,699	+				-0.6
3,556,699	+				+1.2
3,556,699	+				+0.4
3,556,699	+				-0.4
3,556,721	+				+0.9
3,556,780	+				-0.4
3,556,860	+				-1.5
3,556,861	-				-0.1
3,556,945	+		Rv3190A	0.43	+1.7
3,556,945	+		Rv3190A	0.43	-0.3
3,556,946	-		Rv3190A	0.43	+0.6
3,556,962	+		Rv3190A	0.51	-0.8
3,556,963	-		Rv3190A	0.51	+0.6
3,556,981	+		Rv3190A	0.60	-1.2
3,556,981	+		Rv3190A	0.60	+0.8
3,556,981	+		Rv3190A	0.60	+0.3
3,556,982	-		Rv3190A	0.60	-0.4
3,556,982	-		Rv3190A	0.60	-0.3
3,557,037	+		Rv3190A	0.87	-0.3
3,557,038	-		Rv3190A	0.87	+0.7
3,557,111	-				-1.1
3,557,111	-				+0.7
3,557,143	+				-0.5
3,557,144	-				+0.7
3,557,175	+				+1.2
3,557,176	-				-0.5
3,557,251	+				-0.1
3,557,251	+				+0.0
3,557,251	+				-0.6
3,557,252	-				-0.9
3,557,252	-				+0.9
3,557,279	+				+1.3
3,557,280	-				+0.7
3,557,308	+				-0.4
3,557,308	+				-0.2
3,557,308	+				+0.2
3,557,309	-				-0.3
3,557,445	-		Rv3191c	0.13	-0.1
3,557,474	+		Rv3191c	0.16	+0.7
3,557,475	-		Rv3191c	0.16	+0.1
3,557,676	-		Rv3191c	0.35	-0.3
3,557,676	-		Rv3191c	0.35	-0.1